Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir.

Author: AndradeAdriana S A, BrownTodd T, CaballeroBenjamin, DobsAdrian S, FlexnerCharles W, HendrixCraig, ParsonsTeresa L, YuanChun-Su

Paper Details 
Original Abstract of the Article :
Complementary and alternative medicine (CAM) use is prevalent among HIV-infected patients to reduce the toxicity of antiretroviral therapy. Ginseng has been used for treatment of hyperglycemia and insulin resistance, a common side effect of some HIV-1 protease inhibitors (PI). However, it is unknown...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542349/

データ提供:米国国立医学図書館(NLM)

Ginseng and Indinavir: A Potential for Interaction

This study investigates the potential interaction between American ginseng (AG) and the HIV protease inhibitor indinavir (IDV), a drug known to cause hyperglycemia and insulin resistance. The researchers examined the pharmacokinetic and metabolic effects of AG in healthy volunteers receiving IDV therapy, evaluating potential interactions between these two agents.

The findings suggest that AG may have a minor impact on the pharmacokinetics of IDV, but further research is needed to determine whether AG can effectively reverse IDV-induced insulin resistance. This exploration of potential drug interactions is like a desert traveler carefully considering the impact of a new resource on their journey, seeking a balance between benefits and risks.

Navigating the Complexities of Drug Interactions

This study highlights the importance of carefully considering potential drug interactions, especially when using complementary and alternative medicine (CAM) alongside conventional therapies. It's like a camel using its knowledge of desert plants to find safe and beneficial resources while avoiding potentially harmful ones.

A Cautionary Tale: Ginseng and Indinavir

This study underscores the importance of communicating with your healthcare provider about all medications and supplements you are taking, especially when using CAM therapies. It's like a camel using its keen senses to detect changes in the environment, adapting its behavior to ensure survival.

Dr.Camel's Conclusion

This study provides valuable insights into the potential interactions between American ginseng and indinavir. It emphasizes the need for careful monitoring and further research to fully understand the implications of using these two agents together.

Date :
  1. Date Completed 2008-11-24
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18713456

DOI: Digital Object Identifier

PMC2542349

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Languages

English

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