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Ranolazine for chronic stable angina.

Author: NashDavid T, NashStephen D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Ranolazine, a new antianginal drug, has demonstrated efficacy in increasing exercise capacity and reducing anginal episodes. However, potential side effects include dizziness, constipation, nausea, and QT(c) interval prolongation.
Paper Details　
Original Abstract of the Article :
Ranolazine is a new and unique antianginal drug that has been approved for the treatment of chronic stable angina pectoris. The drug is administered as a sustained-release formulation. Although the drug's mechanism of action has not been fully elucidated, current thinking is that ranolazine, a selec...See full text at original site
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引用元：
https://doi.org/10.1016/S0140-6736(08)61554-8

データ提供：米国国立医学図書館（NLM）

Ranolazine: A New Hope for Chronic Stable Angina

Chronic stable angina is a condition characterized by chest pain caused by reduced blood flow to the heart. Ranolazine, a new drug, has been approved for treating this condition. This review summarizes the efficacy and safety of ranolazine in treating chronic stable angina.

Efficacy and Safety of Ranolazine

Clinical trials have demonstrated that ranolazine effectively improves exercise tolerance and reduces anginal episodes. While generally well-tolerated, ranolazine can cause side effects such as dizziness, constipation, and nausea. It can also prolong the QT interval on an electrocardiogram, a measure of heart rhythm, which can be a concern for some patients.

A Valuable Addition to the Angina Arsenal

This review suggests that ranolazine can be a valuable addition to the treatment options for chronic stable angina, particularly in patients who require more aggressive management. Clinicians must carefully assess the risks and benefits of ranolazine for each individual patient, taking into account potential side effects and interactions with other medications.

Dr.Camel's Conclusion

In the desert of cardiovascular disease, we seek effective therapies to alleviate chest pain and improve heart health. Ranolazine offers a new path for treating chronic stable angina, providing relief for many patients. As with all medications, it's important to carefully consider the potential risks and benefits and to work closely with healthcare providers to make informed treatment decisions.
Date :
  1. Date Completed 2008-11-05
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

18929905

DOI: Digital Object Identifier

10.1016/S0140-6736(08)61554-8

Related Literature

Article Analysis
・Side Effects of ranolazine
SNS
PICO Info
in preparation
Languages

English

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