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Effect of praziquantel treatment during pregnancy on cytokine responses to schistosome antigens: results of a randomized, placebo-controlled trial.

Author: DunneDavid W, DuongTrinh, ElliottAlison M, Katunguka-RwakishayaEli, MawaPatrice A, NdibazzaJuliet, Ngom-WegiSophy, TweyongyereRobert, VennervaldBirgitte J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study examines the immunological effects of praziquantel treatment for schistosomiasis during pregnancy. The results show that praziquantel treatment boosts antischistosome responses, with a type 2 helper T cell bias that may contribute to immunologically mediated killing and protection against reinfection.
Paper Details　
Original Abstract of the Article :
Praziquantel treatment of schistosomiasis boosts antischistosome responses, with type 2 helper T cell bias that may contribute to immunologically mediated killing and to protection against reinfection. Praziquantel treatment during pregnancy was recommended in 2002, but the immunological effects of ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://pubmed.ncbi.nlm.nih.gov/18983246

データ提供：米国国立医学図書館（NLM）

Exploring the Immune Response to Schistosomiasis Treatment

Schistosomiasis, a parasitic disease prevalent in many parts of the world, can leave its mark on the immune system. This study investigates the impact of praziquantel treatment during pregnancy on the immune response to schistosome antigens. The researchers conducted a randomized, placebo-controlled trial to assess the effects of praziquantel treatment on cytokine responses in pregnant women infected with schistosomiasis.

Praziquantel's Impact on Immune Responses

The study found that [研究結果]. This finding suggests that [社会的な意義] and provides valuable insights into the immune response to schistosomiasis treatment.

Navigating Schistosomiasis Treatment

The research provides valuable insights for patients and clinicians managing schistosomiasis. The study found that [研究結果]. It is important to discuss potential risks and benefits of schistosomiasis treatment with a healthcare provider and to consider the impact of treatment on the immune system.

Dr.Camel's Conclusion

This study delves into the intricate world of the immune response to schistosomiasis treatment, highlighting the potential impact of praziquantel on cytokine responses during pregnancy. The research underscores the importance of understanding the immune system's dynamics in managing this parasitic disease and its implications for treatment strategies.
Date :
  1. Date Completed 2009-01-16
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

18983246

DOI: Digital Object Identifier

UKMS29620

Related Literature

Article Analysis
・Effects of praziquantel
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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