[Differences among bisfosfonates--specificity of risedronate (Actonel)].

Author: GiljevićZlatko

Paper Details 
Original Abstract of the Article :
Bisphosphonates, a gold standard in therapeutic options for the management of osteoporosis, inhibit bone resorption with relatively few side effects. As a result, they are widely used for the prevention and treatment of osteoporosis. There are clear biochemical and pharmacological differences among ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19024283

データ提供:米国国立医学図書館(NLM)

Risedronate: A Powerful Weapon Against Osteoporosis

The battle against [osteoporosis] is a constant endeavor, and [bisphosphonates] are powerful allies in this fight. This research focuses on the [specific properties of risedronate], a bisphosphonate known for its [inhibition of bone resorption] and its efficacy in preventing and treating osteoporosis.

Risedronate: A Unique Player in the Bisphosphonate Game

The study highlights the [unique characteristics of risedronate] compared to other bisphosphonates. It has a [moderate mineral binding affinity] and a [higher inhibition of famesyl pyrophosphate synthase (FPPS)], a key enzyme involved in bone metabolism. These properties contribute to risedronate's [proven efficacy in preventing vertebral and nonvertebral fractures].

A Strong Defense Against Fractures

The research underscores the [efficacy of risedronate] in [reducing the risk of fractures]. Studies have shown that risedronate can effectively prevent [vertebral and hip fractures] as early as [6 months] after treatment. This makes it a valuable tool in protecting patients from the debilitating consequences of osteoporosis. Think of it like building a sturdy fortress in the desert, shielding individuals from the potential dangers of bone fragility.

Dr.Camel's Conclusion

Risedronate offers a potent and effective solution for preventing and treating osteoporosis. Its unique properties and proven efficacy in reducing fracture risk make it a valuable tool in protecting bone health. Just as a strong camel can navigate the challenging terrain of the desert, risedronate can help individuals maintain their strength and mobility despite the fragility of osteoporosis.

Date :
  1. Date Completed 2008-12-31
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

19024283

DOI: Digital Object Identifier

19024283

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SNS
PICO Info
in preparation
Languages

Croatian

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