Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients.

Author: , BakrisGeorge L, DahlöfBjörn, GatlinMarjorie, GupteJitendra, HesterAllen, JamersonKenneth, PittBertram, ShiVictor, VelazquezEric J, WeberMichael A

Paper Details 
Original Abstract of the Article :
The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend inclusion of a diuretic. We hypothesized that treatment with the combination of an angiotensin-converting-enzyme (ACE) inhibitor and a dihydropyridine calcium-channel blocker would be...See full text at original site
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引用元:
https://doi.org/10.1056/NEJMoa0806182

データ提供:米国国立医学図書館(NLM)

Hypertension: A Silent Threat in the Desert of Cardiovascular Health

Hypertension, a silent but potent force, poses a significant risk to cardiovascular health. Optimal combination drug therapy for hypertension is a subject of ongoing debate and research. This study, published in the journal [Journal Name], investigates the relative effectiveness of two different combination drug therapies for hypertension in high-risk patients.

The study, driven by the hypothesis that an ACE inhibitor and a dihydropyridine calcium-channel blocker combination would be more effective than an ACE inhibitor and a thiazide diuretic combination, enrolled high-risk patients with hypertension. The researchers compared the two combination drug therapies, aiming to determine which approach offered superior cardiovascular protection.

While the study is still ongoing, the initial findings, like a compass pointing us towards a better understanding of hypertension treatment, provide valuable insights into the potential benefits and risks of different drug combinations. The study's findings are crucial for guiding future research and optimizing treatment strategies for hypertension.

Hypertension: A Multifaceted Challenge in Need of Personalized Treatment

This study underscores the importance of individualized treatment strategies for hypertension. The study's findings, though preliminary, offer valuable insights into the potential benefits and risks of different drug combinations. It is essential to work closely with a healthcare professional to develop a personalized treatment plan that addresses individual risk factors and aims to achieve optimal blood pressure control.

Navigating the Desert of Hypertension: A Guide to Effective Management

If you are diagnosed with hypertension, it's crucial to consult with a healthcare professional to discuss the most appropriate treatment options. This study provides valuable insights into the potential benefits and risks of different drug combinations, empowering you to make informed decisions about your care. Lifestyle modifications, such as adopting a healthy diet, exercising regularly, and managing stress, are also essential for managing hypertension and improving overall cardiovascular health.

Dr.Camel's Conclusion

This study, like a caravan traversing the vast desert of cardiovascular health, offers valuable insights into the complex world of hypertension treatment. The research highlights the importance of individualized approaches and emphasizes the need for continued research to refine treatment strategies and optimize outcomes for patients with hypertension.

Date :
  1. Date Completed 2008-12-09
  2. Date Revised 2023-10-24
Further Info :

Pubmed ID

19052124

DOI: Digital Object Identifier

10.1056/NEJMoa0806182

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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