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Effects of ritonavir-boosted darunavir vs. ritonavir-boosted atazanavir on lipid and glucose parameters in HIV-negative, healthy volunteers.
Author: Diego MirallesG, LefebvreE, SekarV, TomakaF, Van BaelenB, VandevoordeA, VangeneugdenT
Original Abstract of the Article :
BACKGROUND: Darunavir (TMC114) is a new HIV protease inhibitor (PI). DESIGN: This Phase I, randomized, open-label trial compared the effects of darunavir plus low-dose ritonavir (RTV) (darunavir/RTV) with those of atazanavir/RTV on lipid and glucose parameters. METHODS: Forty-nine HIV-negative, he...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1468-1293.2008.00690.x
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of HIV Treatment: A Comparison of Protease Inhibitors
HIV treatment, my friend, is a continuous journey through a desert of complex medications and potential side effects. This study investigates the impact of two different protease inhibitors, darunavir and atazanavir, on lipid and glucose parameters in healthy volunteers. It's like comparing two different paths through the desert, each with its own set of challenges and potential rewards.
A Comparison of Paths in the Desert of HIV Treatment
The authors, like skilled guides, compared the effects of darunavir/RTV and atazanavir/RTV on lipid and glucose levels in healthy volunteers. This comparison, like navigating different pathways in the desert, sheds light on the potential advantages and disadvantages of each treatment option.
Finding the Right Path in the Desert
This research helps to inform the decision-making process for HIV treatment, offering a clearer understanding of the potential impact of different protease inhibitors on lipid and glucose parameters. It's like having a reliable map to navigate the desert of HIV treatment, ensuring a safer and more effective journey.
Dr. Camel's Conclusion
This study provides valuable insights into the effects of different protease inhibitors on lipid and glucose levels, offering a clearer picture of the potential consequences of each treatment option. It's a reminder that even in the desert of HIV treatment, where the path can be long and challenging, careful navigation and informed decision-making can lead to a more successful and fulfilling journey.
Date :
- Date Completed 2010-03-12
- Date Revised 2015-11-19
Further Info :
Related Literature
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