Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial.

Author: AgenoWalter, AndersonDavid, BlosteinMark D, ClarkNathan P, CrowtherMark A, DowdMary Beth, GarciaDavid, GinsbergJeffery, KahnSusan R, KearonClive, KovacsMichael J, RodgerMarc A, SchulmanSam, SelbyRita, SilingardiMauro, SiragusaSergio, VeselySara K, WangLuqi, WellsPhillip, WittDan M

Paper Details 
Original Abstract of the Article :
BACKGROUND: Low-dose oral vitamin K decreases the international normalized ratio (INR) in overanticoagulated patients who receive warfarin therapy. Its effects on bleeding events are uncertain. OBJECTIVE: To see whether low-dose oral vitamin K reduces bleeding events over 90 days in patients with w...See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-150-5-200903030-00005

データ提供:米国国立医学図書館(NLM)

Oral Vitamin K Versus Placebo for Correcting Excessive Anticoagulation

This research delves into the complex world of anticoagulants, a world where delicate balance is key. The authors investigate the effects of oral vitamin K, a common treatment for overanticoagulation in patients receiving warfarin therapy. The study is like a scientific expedition, meticulously designed to analyze the impact of vitamin K on various outcomes, including bleeding events and thromboembolism. Their findings reveal that low-dose oral vitamin K does not significantly reduce bleeding events in patients with high INR values, despite its ability to effectively reduce INR levels.

Navigating the Tightrope: A Delicate Balance in Anticoagulation Therapy

The findings illuminate the complexities of anticoagulation therapy, emphasizing the need for cautious consideration of treatment options. It's like navigating a tightrope, where every step requires precision and awareness. The study's results suggest that while vitamin K can effectively reduce INR levels, it may not necessarily mitigate the risk of bleeding, highlighting the need for individualized treatment approaches.

Managing the Risks: A Prudent Approach to Anticoagulation

This research underscores the importance of ongoing monitoring and careful management of patients receiving warfarin therapy. It's like being a desert explorer, always vigilant for potential hazards. Understanding the complexities of anticoagulation and the potential risks associated with specific interventions is crucial in optimizing patient care.

Dr.Camel's Conclusion

This research sheds light on the complex relationship between oral vitamin K and bleeding events in warfarin recipients. It emphasizes the need for a personalized approach to anticoagulation therapy, carefully weighing the potential risks and benefits of treatment options.
Date :
  1. Date Completed 2009-03-25
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

19258557

DOI: Digital Object Identifier

10.7326/0003-4819-150-5-200903030-00005

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Languages

English

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