The role of dosimetry in the high activity 90Y-ibritumomab tiuxetan regimens: two cases of abnormal biodistribution.

Author: AricòDemetrio, CremonesiMarta, FerrariMahila, GranaChiara Maria, MalliaAndrew, MartinelliGiovanni, PaganelliGiovanni, SansoviniMaddalena, VanazziAnna

Paper Details 
Original Abstract of the Article :
Radioimmunotherapy (RIT) with a commercially available brand of yttrium-90 ((90)Y)-ibritumomab-tiuxetan at the prescribed activity of 14.8 MBq/kg (0.4 mCi/kg) represents a complementary approach in the treatment of resistant/refractory B-cell non-Hodgkin's lymphoma. A trial based on higher activitie...See full text at original site
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引用元:
https://doi.org/10.1089/cbr.2008.0541

データ提供:米国国立医学図書館(NLM)

Radioimmunotherapy: A Tailored Approach to Cancer Treatment

This research delves into the world of oncology, specifically focusing on radioimmunotherapy (RIT) with yttrium-90 (90Y)-ibritumomab-tiuxetan, a targeted therapy used to treat resistant/refractory B-cell non-Hodgkin's lymphoma. The study investigates the importance of dosimetry, a crucial aspect of radiation therapy, in optimizing treatment outcomes and minimizing potential side effects. The researchers examine two cases of atypical biodistribution, highlighting the need for individualized dosimetric assessments to ensure safe and effective RIT administration.

Dosimetry: A Crucial Element in Radioimmunotherapy

The study emphasizes the critical role of dosimetry in RIT, underscoring the need for individualized assessments to tailor therapy based on individual patient characteristics. The researchers highlight the potential for atypical biodistribution, which can lead to excessive radiation exposure to certain organs, emphasizing the importance of pre-treatment dosimetry to optimize therapy and minimize potential risks. These findings highlight the need for a personalized approach to RIT, ensuring that patients receive the right dose of radiation to the right targets.

Navigating Cancer Treatment with Precision

This research underscores the importance of personalized medicine in cancer treatment, demonstrating the need for careful planning and individualized assessment to optimize outcomes. By embracing a precision-based approach to RIT, we can maximize the effectiveness of therapy while minimizing potential side effects. This research serves as a reminder that the journey through cancer treatment requires a careful blend of scientific knowledge, patient-centered care, and a commitment to achieving the best possible outcomes.

Dr.Camel's Conclusion

This research illuminates the importance of precision in cancer treatment, emphasizing the need for a tailored approach that considers individual patient characteristics. Just as a camel navigates the shifting sands of the desert, we must adapt our approach to cancer therapy to ensure safe and effective treatment for each patient. This research is a testament to the power of scientific advancements to personalize medicine and improve outcomes for those facing the challenges of cancer.

Date :
  1. Date Completed 2009-08-06
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

19409050

DOI: Digital Object Identifier

10.1089/cbr.2008.0541

Related Literature

SNS
PICO Info
in preparation
Languages

English

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