Adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma: a phase III randomized controlled trial of health-related quality of life and symptoms by the European Organisation for Research and Treatment of Cancer Melanoma Group.

Author: BottomleyAndrew, CoensCorneel, DummerReinhard, EggermontAlexander, GoreMartin, KeilholzUlrich, KruitWillem, KusicZvonko, MackieRona, MarsdenJeremy, PatelPoulam, PuntCornelis, SalèsFrançois, SantinamiMario, SchadendorfDirk, SpatzAlain, SuciuStefan, TestoriAlessandro

Paper Details 
Original Abstract of the Article :
Interferon (IFN) -based adjuvant therapy in melanoma is associated with significant side effects, which necessitates evaluation of health-related quality of life (HRQOL). Our trial examined the HRQOL effects of adjuvant pegylated IFN-alpha-2b (PEG-IFN-alpha-2b) versus observation in patients with st...See full text at original site
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引用元:
https://doi.org/10.1200/JCO.2008.20.2069

データ提供:米国国立医学図書館(NLM)

The Quality of Life Impact of Adjuvant Therapy for Melanoma

Melanoma, a potentially deadly form of skin cancer, requires aggressive treatment strategies. This research investigates the impact of adjuvant therapy with pegylated interferon alfa-2b (PEG-IFN-alpha-2b) on the quality of life (HRQOL) of patients with stage III melanoma. It's like venturing into a desert landscape, exploring the effects of a powerful treatment on the well-being of those affected by cancer.

The Quality of Life Challenge in Melanoma Treatment

The study, conducted by the European Organisation for Research and Treatment of Cancer Melanoma Group, finds that adjuvant therapy with PEG-IFN-alpha-2b can have significant side effects, impacting HRQOL. It's like navigating a desert landscape, where the harsh conditions can take a toll on travelers. The research highlights the need for careful consideration of the potential trade-offs between treatment benefits and quality of life.

Improving Quality of Life in Melanoma Care

This research underscores the importance of addressing HRQOL concerns in melanoma treatment. It's like providing a source of water and shade in a harsh desert, ensuring the well-being of patients undergoing treatment. The study's findings emphasize the need for individualized care plans that prioritize both disease control and quality of life.

Dr.Camel's Conclusion

This research is a reminder that even in the face of serious illness, quality of life matters. The study's findings highlight the need for comprehensive care that addresses both the physical and emotional needs of patients battling melanoma. This research underscores the importance of balancing the fight against cancer with the preservation of patient well-being.

Date :
  1. Date Completed 2009-07-09
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

19433686

DOI: Digital Object Identifier

10.1200/JCO.2008.20.2069

SNS
PICO Info
in preparation
Languages

English

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