Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, sargramostim) administered for 3 years as adjuvant therapy of stages II(T4), III, and IV melanoma.

Author: AllenRobert E, CruickshankScott, GarbeEdeltraut, LinHui-Yi, MeyerJohn, SoongSeng-jaw, SpitlerLynn E, WeberRobert W

Paper Details 
Original Abstract of the Article :
A hypothesis generating study was conducted to evaluate the safety and efficacy of prolonged (3 y) administration of granulocyte-macrophage colony-stimulating factor (GM-CSF, sargramostim) as surgical adjuvant therapy in patients with melanoma at high risk of recurrence. Ninety-eight evaluable patie...See full text at original site
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引用元:
https://doi.org/10.1097/CJI.0b013e3181a7d60d

データ提供:米国国立医学図書館(NLM)

Evaluating the Safety and Efficacy of Prolonged GM-CSF Treatment for Melanoma

Melanoma is a serious form of skin cancer. This research evaluated the safety and efficacy of [prolonged granulocyte-macrophage colony-stimulating factor (GM-CSF) treatment] as adjuvant therapy for patients with melanoma at high risk of recurrence. They conducted a study involving patients with stages II(T4), III, or IV melanoma, administering GM-CSF for 3 years after surgery.

Prolonged GM-CSF Treatment Shows Potential for Melanoma Management

The study found that [prolonged GM-CSF treatment was well tolerated] and showed promising results in terms of disease-free survival. This suggests that GM-CSF could be a valuable tool for managing melanoma and preventing recurrence. It’s like finding a hidden spring in the desert, offering a source of strength and resilience in the fight against melanoma.

Navigating Melanoma Treatment

Melanoma is a challenging disease, but this research offers a glimmer of hope. While further research is needed to confirm the long-term benefits of GM-CSF, the study provides valuable information for clinicians and patients. It’s a reminder that the journey through melanoma treatment can be long and complex, but there are possibilities for finding effective solutions.

Dr. Camel's Conclusion

This research explores the potential of prolonged GM-CSF treatment as adjuvant therapy for melanoma. The study provides evidence for the safety and potential efficacy of this approach, offering hope for those seeking to manage this challenging disease.

Date :
  1. Date Completed 2009-10-05
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

19483646

DOI: Digital Object Identifier

10.1097/CJI.0b013e3181a7d60d

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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