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Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review.
Author: AnnaneDjillali, BellissantEric, BollaertPierre-Edouard, BriegelJosef, ConfalonieriMarco, De GaudioRaffaele, KehDidier, KupferYizhak, MeduriG Umberto, OppertMichael
Original Abstract of the Article :
CONTEXT: The benefit of corticosteroids in severe sepsis and septic shock remains controversial. OBJECTIVE: We examined the benefits and risks of corticosteroid treatment in severe sepsis and septic shock and the influence of dose and duration. DATA SOURCES: We searched the CENTRAL, MEDLINE, EMBAS...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1001/jama.2009.815
データ提供:米国国立医学図書館(NLM)
Corticosteroids in Sepsis: A Desert Oasis or a Mirage?
This research delves into the complex world of sepsis, a life-threatening condition that's like a fierce sandstorm in the body. The study examines the role of corticosteroids in treating severe sepsis and septic shock, trying to determine if they are a life-saving oasis or a misleading mirage.
A Shifting Desert Landscape: The Elusive Benefits of Corticosteroids
For decades, the use of corticosteroids in sepsis has been debated, like navigating a desert where the path is unclear. This study provides a comprehensive analysis of the evidence, revealing that the benefit of corticosteroids on mortality is not as clear-cut as initially thought. However, the study found that prolonged low-dose corticosteroid treatment may be associated with improved short-term survival, potentially offering a ray of hope in the face of this daunting condition.
Navigating the Sandstorms: Balancing Benefits and Risks
The study also notes that while corticosteroids may offer some benefits, they also come with potential risks, such as hyperglycemia and hypernatremia. It's like navigating a desert where a refreshing oasis might also be home to dangerous predators. Careful monitoring and management of these potential side effects are crucial for ensuring safe and effective use of corticosteroids in sepsis.
Dr. Camel's Conclusion
The use of corticosteroids in sepsis is a complex and evolving landscape. This research, like a compass in the desert, helps us navigate the evidence, offering valuable insights into the potential benefits and risks of this treatment approach. It's a reminder that even in the most challenging medical scenarios, ongoing research is crucial for finding the most effective and safest path forward.
Date :
- Date Completed 2009-06-16
- Date Revised 2022-03-11
Further Info :
Related Literature
English
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