Paper Details

  1. Home
  2. Paper Details

Fixed-dose combinations of renin-angiotensin blocking agents with calcium channel blockers or hydrochlorothiazide in the treatment of hypertension.

Author: BramlagePeter

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the evidence for combining angiotensin converting enzyme inhibitors (ACEi) with calcium channel blockers (CCBs) for the treatment of hypertension. The evidence suggests that ACEi/CCB combinations are more effective than ACEi/HCTZ combinations in patients with compelling indications for CCBs. However, further research is needed to determine the role of these drug combinations in a broader patient population.
Paper Details　
Original Abstract of the Article :
Hypertension is a health threat which, so far, is not successfully managed, despite the availability of effective drug treatment. Guidelines recommend drug-drug combinations as a first-line treatment in high-risk patients with severe hypertension, or as an escalation for patients not controlled on m...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1517/14656560903036103

データ提供：米国国立医学図書館（NLM）

The Complexities of Blood Pressure Control: Navigating Drug Combinations

Hypertension, a silent enemy that can lead to heart disease and stroke, is like a desert mirage, often overlooked until it's too late. This study explores the effectiveness of combining renin-angiotensin blocking agents with either calcium channel blockers or hydrochlorothiazide to control blood pressure. The researchers aim to determine the optimal combination therapy for patients with hypertension.

Finding the Right Oasis: Optimal Combinations for Hypertension

The study suggests that combining renin-angiotensin blocking agents with calcium channel blockers might be more effective than combining them with hydrochlorothiazide for certain patients with hypertension. It's like choosing the right path in a desert, selecting the combination therapy that best suits the individual's needs. Further research is needed to determine the optimal approach for a wider range of patients.

Managing Blood Pressure: A Desert of Challenges, A Path to Wellness

This study highlights the complexities of managing hypertension and the importance of personalized treatment plans. It reminds us that managing blood pressure effectively involves finding the right combination of lifestyle changes and medication to control this silent threat. Remember, maintaining good health is like finding a hidden oasis in the desert of life.

Dr. Camel's Conclusion

This study sheds light on the complexities of hypertension management and the potential benefits of combining renin-angiotensin blocking agents with either calcium channel blockers or hydrochlorothiazide. While the combination with calcium channel blockers appears to be more effective in certain patient populations, further research is needed to determine the optimal approach for a wider range of patients with hypertension.
Date :
  1. Date Completed 2009-09-16
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19538001

DOI: Digital Object Identifier

10.1517/14656560903036103

Related Literature

Article Analysis
・Side Effects of benazepril
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.