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Systemic and renal effects of a new angiotensin converting enzyme inhibitor, benazepril, in essential hypertension.

Author: AlbertiD, AntigaL, BedognaV, CasagrandeP, Dal SantoF, MaschioG, PerobelliL, ValvoE, ZamboniM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Benazepril, a new ACE inhibitor, effectively controlled blood pressure in patients with essential hypertension, reducing renal vascular resistance and increasing renal plasma flow.
Paper Details　
Original Abstract of the Article :
Seventeen essential hypertensive patients with normal renal function were treated with a new non-sulphydryl orally active angiotensin converting enzyme (ACE) inhibitor, benazepril, 10 mg given once or twice daily, according to diastolic blood pressure levels, for 6 weeks. In all patients, changes in...See full text at original site
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引用元：
https://doi.org/10.1097/00004872-199011000-00003

データ提供：米国国立医学図書館（NLM）

Systemic and Renal Effects of Benazepril: A Journey Through the Desert of Hypertension

Hypertension, a silent threat that can feel like a relentless sandstorm on the cardiovascular system, requires effective management. This study, like a team of researchers exploring the effects of a new drug, investigates the systemic and renal effects of benazepril, a non-sulphydryl angiotensin converting enzyme (ACE) inhibitor, in patients with essential hypertension. The researchers, like skilled physicians, carefully monitor the effects of benazepril on blood pressure, systemic and renal hemodynamics, and various hormonal markers, seeking to understand its impact on cardiovascular and renal function.

Navigating the Desert of Hypertension: A New Path to Blood Pressure Control

The study demonstrates that benazepril, like a skilled desert guide, effectively controls blood pressure while maintaining normal renal function. The researchers observed a significant decrease in peripheral vascular resistance, a key factor in regulating blood pressure, suggesting that benazepril promotes vasodilation. This is like finding a path through the desert that leads to a more open and less constricted route, promoting a smoother flow of blood throughout the body.

A New Oasis in Hypertension Treatment: Improving Cardiovascular Health

This research offers valuable insights into the potential benefits of benazepril in managing hypertension. It highlights the ability of this drug to control blood pressure while preserving renal function, offering a potential solution for patients navigating the complex terrain of cardiovascular health.

Dr.Camel's Conclusion

This study offers a promising oasis in the desert of hypertension treatment. Benazepril's effectiveness in controlling blood pressure while maintaining renal function provides a valuable option for patients seeking a safe and effective approach to managing this prevalent health condition.
Date :
  1. Date Completed 1991-03-29
  2. Date Revised 2019-08-20
Further Info :

Pubmed ID

1963190

DOI: Digital Object Identifier

10.1097/00004872-199011000-00003

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Languages

English

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