A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis.

Author: CicciaFrancesco, FerranteAngelo, GiardinaAnna Rita, ImpastatoRosalia, MiceliMaria Concetta, PrincipatoAlfonso, TrioloGiovanni

Paper Details 
Original Abstract of the Article :
The signs and symptoms of ankylosing spondylitis (AS) respond inadequately to nonsteroidal antiinflammatory drugs, corticosteroids, and disease modifying antirheumatic drugs in quite a number of patients. Tumor necrosis factor inhibitors have demonstrated to be of value in reducing AS disease activi...See full text at original site
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引用元:
https://doi.org/10.1007/s00296-009-1157-3

データ提供:米国国立医学図書館(NLM)

Etanercept vs. Infliximab: A Comparative Study in Ankylosing Spondylitis

The management of [ankylosing spondylitis (AS)] is a key challenge in [Rheumatology]. This study compares the efficacy and safety of [etanercept] and [infliximab], two [tumor necrosis factor inhibitors], in patients with AS. The researchers conducted a 2-year open-label randomized trial to assess the effectiveness of these treatments.

Infliximab Shows More Rapid Improvement in AS

The study found that treatment with [infliximab] resulted in a significantly more rapid clinical improvement compared to [etanercept]. However, both treatments were effective, safe, and well tolerated at the end of the study. This finding suggests that infliximab may be a more suitable option for patients seeking rapid symptom relief, but both medications offer long-term benefits for managing AS.

Managing AS: Choosing the Right Treatment Path

This study, like a branching desert trail offering different routes to the same destination, highlights the importance of considering individual patient needs when choosing treatment for AS. The findings suggest that infliximab may be a better option for patients seeking a faster response, while etanercept provides a safe and effective alternative. It's a reminder that each patient's journey with AS is unique, and finding the right treatment path is crucial for achieving optimal outcomes.

Dr.Camel's Conclusion

This research is like a camel caravan exploring two different paths across the desert of AS treatment. Both etanercept and infliximab offer relief, but infliximab offers a faster journey to symptom improvement. It's a reminder that even in the vast desert of disease treatment, there are many paths to a better outcome.

Date :
  1. Date Completed 2011-05-17
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19851772

DOI: Digital Object Identifier

10.1007/s00296-009-1157-3

SNS
PICO Info
in preparation
Languages

English

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