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Therapeutic closure of the ductus arteriosus: benefits and limitations.

Author: BoubredFarid, MercantiIsabelle, SimeoniUmberto

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The patency of the ductus arteriosus, a blood vessel connecting the aorta and pulmonary artery, can lead to complications in preterm infants. Indomethacin has been used to close the ductus arteriosus, but ibuprofen may be a safer alternative. More research is needed to determine if early closure of the ductus arteriosus improves outcomes for preterm infants.
Paper Details　
Original Abstract of the Article :
Patency of the ductus arteriosus (PDA), a common complication of preterm birth, has been associated to increased risk for intraventricular cerebral hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia and death. Consequently, prophylactic or curative treatment has been advocated before ...See full text at original site
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引用元：
https://doi.org/10.1080/14767050903198132

データ提供：米国国立医学図書館（NLM）

Closing the Ductus Arteriosus: A Balancing Act in Neonatal Care

This study delves into the world of [neonatal medicine], focusing on the management of [patent ductus arteriosus (PDA)], a common complication in premature infants. The authors examine the potential benefits and limitations of [therapeutic closure] of the PDA, both through [pharmacological agents] and [surgical closure]. They highlight the association of PDA with increased risk of complications such as [intraventricular cerebral hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia, and death]. The study emphasizes the need for cautious and individualized approaches to PDA closure, carefully weighing the potential benefits and risks.

Navigating the Delicate Balance: A Weighing of Risks and Benefits

The research suggests that while [pharmacological closure] of the PDA can be effective, it is important to consider potential side effects, such as [renal and cerebral hemodynamic problems]. The authors call for more robust research to evaluate the long-term benefits of PDA closure.

The Oasis of Healthy Development: Protecting Premature Infants

This research underscores the importance of providing optimal care for premature infants, including careful management of PDA. The findings emphasize the need for a balanced approach, weighing the potential benefits of PDA closure against the risks of treatment.

Dr. Camel's Conclusion

The delicate journey of a premature infant through the desert of life requires careful attention and informed decisions. This research sheds light on the complex world of PDA management, reminding us of the importance of balancing benefits and risks to ensure the best possible outcomes for these vulnerable newborns.

Date :
  1. Date Completed 2010-05-19
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

19925358

DOI: Digital Object Identifier

10.1080/14767050903198132

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