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The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline.

Author: AmmiratiMario, AndrewsDavid W, AsherAnthony L, BurriStuart H, CobbsCharles S, GasparLaurie E, KalkanisSteven N, KondziolkaDouglas, LinskeyMark E, LoefflerJay S, McDermottMichael, MehtaMinesh P, MikkelsenTom, OlsonJeffrey J, PaleologosNina A, PatchellRoy A, RobinsonPaula D, RykenTimothy C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Corticosteroids are recommended for temporary symptomatic relief of symptoms related to increased intracranial pressure and edema secondary to brain metastases. Dexamethasone is the preferred steroid, and doses should be tailored to symptom severity.
Paper Details　
Original Abstract of the Article :
QUESTION: Do steroids improve neurologic symptoms in patients with metastatic brain tumors compared to no treatment? If steroids are given, what dose should be used? Comparisons include: (1) steroid therapy versus none. (2) comparison of different doses of steroid therapy. TARGET POPULATION: These ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808527/

データ提供：米国国立医学図書館（NLM）

The Role of Steroids in Managing Brain Metastases

This research provides a systematic review and evidence-based clinical practice guideline on the use of steroids for managing brain metastases. The authors analyzed existing studies to determine the effectiveness of steroids in reducing neurologic symptoms associated with brain metastases. Their recommendations focus on the appropriate use of steroids, including dosage and duration of treatment, based on the severity of symptoms.

A Complex and Delicate Landscape

The authors navigate the complex and delicate landscape of treating brain metastases. This is like a camel traversing a treacherous desert, requiring careful planning and execution. The authors offer valuable guidance for clinicians in navigating the challenges of managing brain metastases with the aid of steroids.

Navigating the Treatment Path

The authors' research provides a clear roadmap for managing brain metastases. They offer evidence-based recommendations for the appropriate use of steroids, emphasizing the need for individualized treatment plans tailored to the patient's specific symptoms and overall health. This is like a camel using a map to navigate a vast and unforgiving desert, ensuring that it reaches its destination safely and efficiently.

Dr.Camel's Conclusion

This research offers a comprehensive guide for clinicians in managing brain metastases. The authors provide evidence-based recommendations for the appropriate use of steroids, emphasizing the need for individualized treatment plans. It's essential to approach the treatment of brain metastases with a well-defined plan, ensuring that the benefits of steroid therapy outweigh the potential risks. Just as a camel navigates the desert with a combination of skill and knowledge, healthcare professionals need to be equipped with the necessary tools and knowledge to effectively manage brain metastases, providing patients with the best possible care.
Date :
  1. Date Completed 2010-03-24
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

19957014

DOI: Digital Object Identifier

PMC2808527

Related Literature

Article Analysis
・Effective treatment of steroids
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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