Paper Details

  1. Home
  2. Paper Details

Early treatment with N-acetylcysteine in children with acute liver failure secondary to hepatitis A.

Author: DhanakottiNagasharmila, GonzalezAlejandro, SoteloNorberto, de los Angeles DurazoMaría

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Oral NAC appears to be an effective treatment for hepatitis A-induced liver failure. It can modify the clinical course to a favorable one and prevent the fatal outcome of hepatic encephalopathy.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Hepatitis A virus can evolve to acute liver failure with a fatal outcome if it is not reversed. OBJECTIVE: We describe the clinical course of 12 children who presented with hepatitis A acute liver failure and received treatment with oral N-acetylcysteine (NAC). MATERIALS AND METHODS:...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/20009135

データ提供：米国国立医学図書館（NLM）

N-Acetylcysteine: A Potential Treatment for Hepatitis A Liver Failure

Hepatitis A, a viral infection that affects the liver, can sometimes lead to acute liver failure, a life-threatening condition. This study explores the use of N-acetylcysteine (NAC), a medication commonly used to treat acetaminophen overdose, as a treatment option for hepatitis A-induced liver failure in children.

The researchers analyzed the clinical course of 12 children with hepatitis A-induced liver failure who received oral NAC treatment. They found that all 12 patients showed clinical and laboratory improvement, with significant reductions in liver enzymes, prothrombin time, and ammonia levels. These findings suggest that NAC may be an effective treatment for hepatitis A liver failure in children.

NAC: A Promising Therapy for Liver Failure

While this study offers promising evidence for the potential benefits of NAC in treating hepatitis A liver failure in children, it is important to note that the study was small and further research is needed to confirm these findings. The study also highlights the importance of early intervention and prompt treatment for liver failure to improve outcomes.

Early Detection and Treatment: Keys to Liver Health

This study emphasizes the importance of early detection and prompt treatment for liver failure, especially in children. Regular medical checkups and prompt attention to any signs of liver dysfunction are crucial for preventing serious complications. If you have any concerns about liver health, it's essential to consult with a healthcare professional immediately.

Dr.Camel's Conclusion

This study sheds light on the potential of NAC for treating hepatitis A liver failure in children. Just as a camel's liver efficiently processes water and nutrients in the desert, we must prioritize liver health and seek prompt treatment for any liver-related issues. Early intervention and proper medical care are crucial for safeguarding our vital organs and ensuring overall well-being.

Date :
  1. Date Completed 2010-06-15
  2. Date Revised 2019-09-19
Further Info :

Pubmed ID

20009135

DOI: Digital Object Identifier

S1665-2681(19)31749-1

Related Literature

Article Analysis
・Effective treatment of hepatitis a
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.