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[Thienopyridines in the treatment and prevention of cardiovascular diseases. III. therapeutic application of clopidogrel as monotherapy (without acetylsalicylic acid)].
Author: AvsarO, BatyralievT A, FettserD V, IslekM, PreobrazhenskiĭD V, SidorenkoB A, VuralA
Original Abstract of the Article :
In a series of articles the authors consider clinical pharmacology and experience of clinical application of blockers of platelet P2Y12 receptors, most well known representatives of which ticlopidine and clopidogrel according to chemical structure belong to thienopyridine derivatives. In the third c...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/20038285
データ提供:米国国立医学図書館(NLM)
Clopidogrel: A Powerful Ally in the Fight Against Cardiovascular Disease
The world of [cardiovascular disease] is a labyrinth of complex interactions, much like a desert with its hidden currents and shifting sands. This research explores the use of [clopidogrel], a [platelet P2Y12 receptor blocker], as a [monotherapy] for [cardiovascular disease]. The study aimed to compare the [efficacy and safety] of clopidogrel to other [antiplatelet therapies] such as [acetylsalicylic acid (ASA), ticlopidine, and warfarin].
A Comparison of Antiplatelet Therapies
The study found that [clopidogrel monotherapy] demonstrated [comparable efficacy] to other [antiplatelet therapies]. However, [clopidogrel] was associated with a [significantly lower incidence] of [ulcerogenic and hemorrhagic complications] compared to [ticlopidine]. The study also noted that [clopidogrel] is [more expensive] than other options.
Navigating the Crossroads of Cost and Effectiveness
This research highlights the need for [careful consideration] of both [cost] and [efficacy] when selecting an [antiplatelet therapy]. While [clopidogrel] offers [comparable efficacy] and [improved safety] compared to [ticlopidine], its [higher cost] must be weighed against these benefits. The choice of treatment should be tailored to the [individual patient's needs] and [risk factors].
Dr.Camel's Conclusion
Just as a camel must choose its path carefully through a desert landscape, patients with cardiovascular disease must navigate the complex world of antiplatelet therapies. This research provides valuable insights into the effectiveness and safety of clopidogrel, emphasizing the importance of a personalized approach to treatment decisions.
Date :
- Date Completed 2010-07-09
- Date Revised 2018-12-01
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