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Cerebellum structure differences and relationship to speech in boys and girls with nonsyndromic cleft of the lip and/or palate.

Author: AxelsonEric, CanadyJohn, ConradAmy L, DaileyScott, KarnellMichael P, NopoulosPeg, RichmanLynn

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This study compared cerebellar volume in 43 children with nonsyndromic cleft of the lip and/or palate to 43 healthy controls. Boys with cleft lip and/or palate had smaller cerebellums than controls, while girls only showed regional differences. Cerebellum size was correlated with articulation in boys. These findings suggest that the cerebellum may play a role in speech deficits in children with cleft lip and/or palate.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To identify regional cerebellar structural differences in boys and girls with nonsyndromic cleft of the lip and/or palate and determine whether these differences are related to speech impairment. DESIGN: Between 2003 and 2007, measures on cerebellar volume were obtained on 43 children wi...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/20180711

データ提供：米国国立医学図書館（NLM）

Cerebellum and Speech: A Connection in Children with Cleft Palate

Cleft lip and palate are birth defects that can affect speech development. This study investigates potential structural differences in the cerebellum, a brain region involved in motor coordination and speech, in children with nonsyndromic cleft lip and/or palate. The researchers aimed to identify cerebellar structural differences and explore their relationship to speech impairment.

Cerebellar Differences and Speech Impairment

The study found that boys with nonsyndromic cleft lip and/or palate had smaller cerebellums compared to controls. Regional cerebellar differences were also observed in girls. Importantly, cerebellum size was correlated with articulation in boys, suggesting a possible link between cerebellar structure and speech difficulties.

Understanding the Role of the Cerebellum in Speech

This study provides valuable insights into the potential role of the cerebellum in speech development and the impact of cleft lip and/or palate on brain structure. Further research is needed to fully understand the complex relationship between the cerebellum and speech in these children. Imagine a desert traveler navigating a winding path, where the terrain can impact their journey. The cerebellum could be like the terrain, influencing speech development in children with cleft lip and/or palate.

Dr.Camel's Conclusion

This research offers a glimpse into the intricate connections between brain structure and speech development. It's a reminder that the human brain is a complex and fascinating organ, with subtle differences that can have a significant impact on function.

Date :
  1. Date Completed 2014-04-24
  2. Date Revised 2023-11-04
Further Info :

Pubmed ID

20180711

DOI: Digital Object Identifier

NIHMS333227

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Languages

English

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