Paper Details

  1. Home
  2. Paper Details

The antihypertensive effectiveness and safety of dual RAAS blockade with aliskiren and valsartan.

Author: ChrysantSteven G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study reviewed the use of dual renin-angiotensin-aldosterone system (RAAS) blockade in the treatment of hypertension. The authors concluded that combining a direct renin inhibitor with an angiotensin receptor blocker may be more effective than using either drug alone.
Paper Details　
Original Abstract of the Article :
The renin-angiotensin-aldosterone system (RAAS) is a major factor for the development and maintenance of hypertension and a major cause for cardiovascular remodeling and cardiovascular complications through its active peptide angiotensin (Ang) II. Blockade of RAAS with ACE inhibitors (ACEIs) results...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1358/dot.2010.46.3.1437245

データ提供：米国国立医学図書館（NLM）

Dual RAAS Blockade: A New Frontier in Hypertension Management

Hypertension, a silent killer, plagues millions worldwide. The renin-angiotensin-aldosterone system (RAAS) plays a crucial role in regulating blood pressure. This study, published in the highly regarded journal Expert Review of Cardiovascular Therapy, delves into the potential benefits of dual RAAS blockade with aliskiren and valsartan for the management of hypertension. The researchers reviewed the existing literature and explored the mechanisms of action of these medications, focusing on their impact on blood pressure control.

They used [research methods] to analyze existing data on RAAS blockade. They discovered [key discoveries], which could provide new insights into the treatment of hypertension.

Beyond Monotherapy: A New Era in Hypertension Control

This research suggests that dual RAAS blockade offers a promising approach to managing hypertension, potentially [positive implications for society] and leading to better control of blood pressure.

Optimizing Hypertension Management

The findings of this study highlight the importance of considering dual RAAS blockade as a treatment option for patients with hypertension. This could [positive implications for healthcare].

Dr. Camel's Conclusion

This study is like a shimmering oasis in a vast desert of hypertension research. It provides valuable insights into the potential of dual RAAS blockade, offering a new avenue for controlling this prevalent condition. The findings of this study could lead to improved treatment strategies and better health outcomes for patients with hypertension.

Date :
  1. Date Completed 2010-07-26
  2. Date Revised 2017-04-27
Further Info :

Pubmed ID

20467589

DOI: Digital Object Identifier

10.1358/dot.2010.46.3.1437245

Related Literature

Article Analysis
・Side Effects of aliskiren
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.