Artemisinin-based combination therapies and their introduction in Japan.

Author: KanoShigeyuki

Paper Details 
Original Abstract of the Article :
Artemisinin was discovered in 1971 from a herb, Artemisia annua, which had been used for more than 2,000 years in China against intermittent fever. Now, the artemisinin and its derivatives have become essential components of artemisinin-based combination therapies (ACTs). The ACTs are the recommende...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/20535521

データ提供:米国国立医学図書館(NLM)

Artemisinin-Based Combination Therapies: A New Era in Malaria Treatment

Malaria, a disease that has plagued humanity for centuries, continues to pose a significant threat, particularly in tropical regions. This research explores the potential of artemisinin-based combination therapies (ACTs) as a formidable weapon against malaria. The researchers investigated the efficacy and safety of ACTs, which have become the first-line treatment for malaria due to their rapid parasite clearance and fewer adverse effects.

A Global Challenge, a Global Solution

The researchers emphasize the urgent need for ACTs to be readily available worldwide, especially in countries with high malaria burdens. They highlight the importance of ACTs in treating severe and complicated cases of falciparum malaria, including cerebral malaria, a particularly dangerous form of the disease. The researchers also stress the importance of addressing the increasing resistance to ACTs, which underscores the ongoing need for research and development in this field.

A Collaborative Effort to Conquer Malaria

This research serves as a reminder of the global challenge posed by malaria and the critical role of ACTs in combatting this disease. The research findings encourage continued collaboration among scientists, clinicians, and policymakers to ensure that ACTs are accessible to all who need them, and that the fight against malaria is won.

Dr. Camel's Conclusion

ACTs are like a powerful antidote against the venomous sting of malaria, offering a glimmer of hope in a battle that has raged for millennia. Their rapid parasite clearance and reduced side effects make them a vital weapon in the fight against this devastating disease. However, we must remain vigilant in our efforts to develop new and effective treatments to counter the ever-evolving threat of drug resistance.
Date :
  1. Date Completed 2011-03-22
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20535521

DOI: Digital Object Identifier

S1341-321X(10)70558-4

SNS
PICO Info
in preparation
Languages

English

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