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Combating evolution with intelligent design: the neoglycoside ACHN-490.

Author: ArmstrongEliana S, MillerGeorge H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

ACHN-490, the first neoglycoside, shows promising in vitro activity against wild-type and resistant bacteria, suggesting its potential to address the growing need for new antibacterial agents.
Paper Details　
Original Abstract of the Article :
The challenge posed by increasing levels of drug-resistant bacteria world-wide is manifest, and must be dealt with both by new approaches to the use of existing antibiotics and by the introduction of novel drugs. ACHN-490 is the first neoglycoside, or next-generation aminoglycoside, to begin clinica...See full text at original site
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引用元：
https://doi.org/10.1016/j.mib.2010.09.004

データ提供：米国国立医学図書館（NLM）

Fighting Drug-Resistant Bacteria with Intelligent Design: The Neoglycoside ACHN-490

The emergence of drug-resistant bacteria presents a significant challenge to public health, This research explores a novel approach to combatting antibiotic resistance with the development of a neoglycoside called ACHN-490. This new generation aminoglycoside was specifically designed to target key pathogens, including those resistant to older antibiotics.

A Promising New Weapon in the Fight Against Antibiotic Resistance

ACNH-490 exhibits promising in vitro activity against both wild-type and resistant bacteria. The study highlights the potential of this neoglycoside to overcome antibiotic resistance and provide a valuable tool for treating infections caused by resistant pathogens.

Hope on the Horizon for Treating Resistant Infections

The development of ACHN-490 offers hope for tackling the growing challenge of antibiotic resistance. This research reinforces the need for continuous innovation in the development of new antibiotics to combat resistant strains of bacteria.

Dr.Camel's Conclusion

Like a camel adapting to survive in harsh desert environments, scientists are constantly striving to overcome challenges posed by resistant bacteria. This study showcases a promising new approach to combating antibiotic resistance, offering hope for a future where we can effectively treat even the most resistant infections.

Date :
  1. Date Completed 2010-12-30
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

20932796

DOI: Digital Object Identifier

10.1016/j.mib.2010.09.004

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Languages

English

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