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Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets.
Author: BeenaP, BijeshPv, RemyaKs, SheebaA
Original Abstract of the Article :
The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present study were sodium starch glycolate and crosscarmellose sodium. The formulated tablet...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964761/
データ提供:米国国立医学図書館(NLM)
Exploring the Impact of Superdisintegrants in Oral Disintegrating Tablets
The world of pharmaceuticals is always looking for new ways to make medications more effective and easier to take. This study delves into the fascinating world of superdisintegrants, substances that help medications break down quickly in the body. The researchers focused on their use in developing oral disintegrating tablets, which are meant to dissolve rapidly in the mouth. They compared two popular superdisintegrants, sodium starch glycolate and crosscarmellose sodium, to see which one would create the best tablets. The study evaluated various aspects of the tablets, such as their hardness, thickness, and how quickly they dissolved. The findings revealed that crosscarmellose sodium emerged as the superior choice in creating these dissolvable tablets, potentially making a significant impact on how certain medications are delivered and absorbed.
Crosscarmellose Sodium: A Superior Choice for Oral Disintegrating Tablets
The research indicates that tablets formulated with crosscarmellose sodium excelled in terms of disintegration time and dissolution rate, indicating that they broke down faster and released the medication more efficiently. This suggests that crosscarmellose sodium could be a valuable tool in improving the effectiveness of certain medications, potentially leading to faster symptom relief and improved patient outcomes.
Benefits of Faster Drug Delivery for Patients
This research highlights the importance of understanding how different ingredients influence the way medications are absorbed. The faster disintegration and dissolution of tablets with crosscarmellose sodium could lead to faster drug delivery and potentially more effective treatment. This could be particularly beneficial for patients who have difficulty swallowing pills, as these tablets dissolve in the mouth, making them easier to take.
Dr.Camel's Conclusion
This research emphasizes the importance of researching and optimizing the ingredients used in medications, as it can significantly impact their effectiveness and ease of use. The findings suggest that crosscarmellose sodium could be a game-changer in creating better oral disintegrating tablets, potentially improving the lives of many people. It's like discovering a new oasis in the vast desert of pharmaceutical research, promising a refreshing and efficient way to deliver medication.
Date :
- Date Completed 2011-07-14
- Date Revised 2022-03-10
Further Info :
Related Literature
English
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