A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil.

Author: BartkoSusan J, BusseyTimothy J, SaksidaLisa M, VendrellIgnasi

Paper Details 
Original Abstract of the Article :
Performance on the Cambridge Neuropsychological Test Automated Battery touchscreen paired-associates learning (PAL) test is predictive of Alzheimer's disease and impaired in schizophrenia and chronic drug users. An automated computer touchscreen PAL task for rats has been previously established. A p...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s00213-010-2050-1

データ提供:米国国立医学図書館(NLM)

A Computer-Automated Touchscreen Paired-Associates Learning (PAL) Task for Mice

The study of cognitive function in animals is a fascinating journey through the intricate workings of the mind. This study develops a computer-automated touchscreen paired-associates learning (PAL) task for mice, providing a valuable tool for investigating cognitive processes in this model organism. The researchers, like engineers building a sophisticated device, designed a touchscreen-based PAL task that allows for precise measurement of learning and memory performance in mice.

A New Tool for Understanding Cognition in Mice

The development of this computer-automated touchscreen PAL task provides researchers with a valuable tool for studying cognitive processes in mice. This task can be used to investigate the effects of various drugs, genetic manipulations, and environmental factors on learning and memory in this widely used model organism.

Advancing Our Understanding of Cognitive Function

This study contributes to the development of advanced research methods for studying cognitive function in animals. The availability of this computer-automated touchscreen PAL task for mice provides researchers with a powerful tool for exploring the neural mechanisms underlying learning and memory, potentially leading to new insights into the treatment of cognitive disorders.

Dr.Camel's Conclusion

The mind of a mouse, like a vast desert, holds many secrets waiting to be uncovered. This study provides researchers with a new tool for exploring those secrets, potentially leading to a deeper understanding of cognition and the development of new treatments for cognitive disorders. The journey of scientific discovery is never-ending, and each new tool and technique helps us to navigate the complexities of the mind with greater precision and understanding.

Date :
  1. Date Completed 2011-06-28
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21086119

DOI: Digital Object Identifier

10.1007/s00213-010-2050-1

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.