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Milnacipran for the management of fibromyalgia syndrome.
Author: BoomershineChad S, EylerAnne E, HammondsCara L, OrmsethMichelle J
Original Abstract of the Article :
Fibromyalgia syndrome (FMS) is a widespread pain condition associated with fatigue, cognitive dysfunction, sleep disturbance, depression, anxiety, and stiffness. Milnacipran is one of three medications currently approved by the Food and Drug Administration in the United States for the management of ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004654/
データ提供:米国国立医学図書館(NLM)
Milnacipran: A New Oasis in the Desert of Fibromyalgia Syndrome
Fibromyalgia syndrome (FMS) is a chronic condition characterized by widespread musculoskeletal pain, fatigue, and a host of other debilitating symptoms. This research examines the potential of milnacipran, a medication approved by the Food and Drug Administration for the treatment of adult FMS patients. The authors provide a comprehensive review of milnacipran, outlining its pharmacology, pharmacokinetics, and safety profile. Milnacipran is a mixed serotonin and norepinephrine reuptake inhibitor, targeting neurotransmitters involved in pain perception and mood regulation. The authors highlight milnacipran's proven efficacy in managing global FMS symptoms, including pain, fatigue, and cognitive dysfunction. Furthermore, they emphasize its potential benefits for FMS patients with coexisting depression. However, they also acknowledge the potential for side effects, including headache, nausea, and an increased risk of bleeding and suicidality in at-risk patients. The authors advocate for a cautious approach to milnacipran therapy, recommending low-dose initiation and slow titration to maximize tolerability.
Milnacipran: A Promising New Treatment for FMS
This research provides a thorough evaluation of milnacipran as a treatment option for FMS. The authors highlight milnacipran's efficacy in managing a wide range of FMS symptoms, including pain, fatigue, and cognitive dysfunction. They also acknowledge the potential for side effects but advocate for careful management to maximize tolerability.
The Importance of a Multifaceted Approach to FMS Management
This research emphasizes the importance of a multifaceted approach to FMS management. The authors recommend combining milnacipran with other therapeutic modalities, including exercise, patient education, and behavioral therapies, to optimize outcomes for patients.
Dr.Camel's Conclusion
This research offers a valuable resource for understanding the role of milnacipran in FMS management. The authors' insights provide a roadmap for navigating the complexities of this chronic condition, offering hope for patients seeking relief from its debilitating symptoms.
Date :
- Date Completed 2011-07-14
- Date Revised 2021-10-20
Further Info :
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