[Desmopressin for nocturia in the old: an inappropriate treatment due to the high risk of side-effects?].

Author: ClaassenJ A H R, ReichertL J M, ten DoesschateT

Paper Details 
Original Abstract of the Article :
Desmopressin, a synthetic analog of the antidiuretic hormone, is used in the treatment of enuresis nocturna in children and increasingly also in adults. Nocturia in the elderly causes sleeping disorders and is associated with a higher risk of falling and increased mortality. Desmopressin leads to a ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/21229778

データ提供:米国国立医学図書館(NLM)

Desmopressin for Nocturia in the Elderly: A Cautious Approach

Navigating the complexities of aging and its associated health challenges is a constant journey for healthcare professionals. This study explores the use of desmopressin, a synthetic analog of the antidiuretic hormone, for treating nocturia in the elderly. The authors caution against its indiscriminate use due to the potential for serious side effects, particularly hyponatremia. They present two cases where desmopressin led to hyponatremia, highlighting the importance of careful monitoring and alternative treatment strategies.

Weighing the Risks and Benefits of Desmopressin

The study's findings suggest that desmopressin, despite its potential benefits in reducing nocturia, carries a significant risk of hyponatremia, especially in older adults. This underscores the need for a comprehensive assessment of individual risk factors before prescribing desmopressin. The study emphasizes the importance of considering alternative treatment options and closely monitoring serum sodium levels in patients who are prescribed desmopressin.

Living with Nocturia

Nocturia, a common complaint among older adults, can significantly impact sleep quality and overall well-being. It's important for individuals experiencing nocturia to consult with a healthcare professional to identify the underlying cause and discuss appropriate treatment options. This may involve lifestyle modifications, medications, or other interventions tailored to individual needs.

Dr.Camel's Conclusion

This study provides valuable insights into the use of desmopressin for treating nocturia in the elderly. While desmopressin can be effective in reducing nocturnal urination, it carries a risk of hyponatremia, especially in older adults. This underscores the need for a careful evaluation of individual risk factors and the importance of considering alternative treatment strategies.

Date :
  1. Date Completed 2011-02-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21229778

DOI: Digital Object Identifier

21229778

Related Literature

SNS
PICO Info
in preparation
Languages

Dutch

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