The use of protriptyline for respiratory failure in patients with chronic airflow limitation.

Author: BranthwaiteM A, CarrollN, ParkerR A

Paper Details 
Original Abstract of the Article :
Treatment of nocturnal hypoventilation in patients with restrictive chest wall disease and respiratory failure, results in improved daytime arterial blood gas tensions, increase in functional ability and longer survival. Success has been achieved with the use of protriptyline which reduces the durat...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2124540

データ提供:米国国立医学図書館(NLM)

Protriptyline: A Potential Solution for Respiratory Failure in Chronic Airflow Limitation

Chronic airflow limitation (CAL), a debilitating respiratory condition, is like a desert sandstorm, causing difficulty breathing and limiting everyday activities. This research examines the potential benefits of protriptyline, a tricyclic antidepressant, in treating nocturnal hypoventilation, a common complication of CAL. It's like discovering a new remedy for a persistent desert ailment, offering a potential solution to a challenging health condition.

Protriptyline: A Potential Oasis for Nocturnal Hypoventilation

The study suggests that protriptyline may be effective in reducing the duration of rapid eye movement (REM) sleep, a stage of sleep where nocturnal hypoventilation often occurs. It’s like finding a way to control the desert wind, reducing the impact of a sandstorm. The researchers observed a significant reduction in daytime carbon dioxide levels and an improvement in respiratory muscle strength in patients treated with protriptyline. However, the study also highlights the importance of considering potential side effects, such as anticholinergic effects, which could limit its long-term use.

Managing CAL: Finding the Right Path to Relief

This research provides valuable insights into the potential benefits of protriptyline in managing nocturnal hypoventilation in patients with CAL. It’s like finding a new route across the desert, offering a path to relief from this challenging condition. The study emphasizes the importance of individualized treatment approaches and careful monitoring for potential side effects. Patients with CAL should consult with their healthcare providers to discuss the best treatment options for their individual needs.

Dr.Camel's Conclusion

This research is a reminder that even in the face of complex health challenges, there is always hope for new and innovative solutions. The study underscores the importance of exploring different therapeutic approaches and considering the unique needs of each patient. It's a testament to the ongoing quest for better treatments and improved quality of life for individuals with chronic conditions.

Date :
  1. Date Completed 1991-02-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2124540

DOI: Digital Object Identifier

2124540

Related Literature

SNS
PICO Info
in preparation
Languages

English

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