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Aromatase inhibitor exemestane has antiproliferative effects on human mesothelioma cells.
Author: BaldiAlfonso, BiroccioAnnamaria, D'AngeloCarmen, GalatiRossella, MutiPaola, SacchiAda, SalvatoriLuisa, StoppoloniDaniela, VerdinaAlessandra, VincenziBruno
Original Abstract of the Article :
PURPOSE: The aim of this study was to investigate the expression and biological activity of aromatase (CYP19A1) in malignant mesothelioma (MM). EXPERIMENTAL DESIGN: We found CYP19A1 in five human MM cell lines using reverse transcription polymerase chain reaction and Western immunoblots and in a gr...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/21289517
データ提供:米国国立医学図書館(NLM)
Aromatase Inhibitors and Mesothelioma: A Camel's Perspective on a New Path
The desert of cancer research is constantly evolving, and we're always searching for new paths to victory. This study investigates the potential role of aromatase inhibitors, such as exemestane, in treating malignant mesothelioma. The researchers found that aromatase, an enzyme involved in estrogen production, is expressed in mesothelioma cells, suggesting a potential link between estrogen and tumor growth. They demonstrated that exemestane, an aromatase inhibitor, effectively inhibited the growth of mesothelioma cells in vitro, suggesting a potential new therapeutic strategy.
Exemestane: A Refreshing Oasis in the Desert of Mesothelioma Treatment
This study offers a promising new avenue for treating mesothelioma. It's like finding a refreshing oasis in the desert – exemestane may provide a new path toward managing this aggressive and challenging cancer. The study's findings suggest that aromatase inhibitors may play a significant role in future therapies for mesothelioma.
Navigating the Sands of Cancer Research
Cancer research is a vast and complex desert, and we need to be innovative and adaptable in our approach. This study exemplifies the ongoing search for new treatments and therapies to combat cancer. It's a reminder that we need to be persistent and open-minded in our pursuit of effective therapies.
Dr. Camel's Conclusion
The desert of cancer research is vast and complex. This study offers a promising new path, suggesting that aromatase inhibitors may play a valuable role in treating mesothelioma. It's a reminder that ongoing research and exploration of new therapies are crucial for navigating the challenges of cancer and finding oases of hope for patients.
Date :
- Date Completed 2011-06-21
- Date Revised 2016-11-25
Further Info :
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English
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