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Slow infusion metoclopramide does not affect the improvement rate of nausea while reducing akathisia and sedation incidence.
Author: AydinBerrin, ErdurBulent, ParlakIsmet, TuraPinar, TurkcuerIbrahim
Original Abstract of the Article :
OBJECTIVE: To compare the effects of metoclopramide infusion in emergency department (ED) patients complaining of nausea to determine the changes in its therapeutic effect and prevention of side effects such as akathisia and sedation. METHODS: A prospective, randomised, double blind trial, from 1 M...See full text at original site
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引用元:
https://doi.org/10.1136/emj.2010.094367
データ提供:米国国立医学図書館(NLM)
Metoclopramide: Finding the Sweet Spot for Nausea Relief
Metoclopramide, a medication commonly used to treat nausea and vomiting, can cause side effects such as akathisia (restlessness) and sedation. This study compares the effects of slow intravenous infusion versus bolus intravenous injection of metoclopramide in patients with nausea.
Slow Infusion: A More Comfortable Option
The study, a randomized double-blind trial, demonstrates that slow intravenous infusion of metoclopramide is associated with a significantly lower incidence of akathisia and sedation compared to bolus injection, without affecting the effectiveness of nausea relief. These findings suggest that slow infusion may be a more comfortable and tolerable approach for patients receiving metoclopramide.
Optimizing Patient Comfort and Treatment Effectiveness
This research emphasizes the importance of optimizing patient comfort and treatment effectiveness by considering different administration routes and dosages. The study highlights the value of exploring alternative approaches to medication delivery, potentially leading to improved patient experience and adherence to treatment.
Dr.Camel's Conclusion
Just as a camel carefully chooses its path through the desert to avoid obstacles, researchers are constantly seeking ways to optimize patient care. This study offers valuable insights into the impact of administration methods on the effectiveness and tolerability of metoclopramide. The findings emphasize the importance of individualizing treatment approaches to maximize benefits and minimize side effects.
Date :
- Date Completed 2012-03-12
- Date Revised 2013-11-21
Further Info :
Related Literature
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