Clinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitis.

Author: BohetsHilde, Edwards-SwansonKimberly, MannensGeert, McGowanClaude, SchroederNathalie, ShapiroAron

Paper Details 
Original Abstract of the Article :
PURPOSE: In this report, we characterize the in vitro pharmacokinetic properties of a new antihistamine, alcaftadine. In addition, we report results from phase 1 studies of several ophthalmic formulations of alcaftadine and examine the pharmacokinetic properties of one formulation in detail. METHOD...See full text at original site
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引用元:
https://doi.org/10.1089/jop.2010.0153

データ提供:米国国立医学図書館(NLM)

Alcaftadine: A Novel Antihistamine for Allergic Conjunctivitis

The realm of allergies is a vast and challenging desert, with individuals constantly seeking relief from the irritating and often debilitating symptoms. This study explores the potential of alcaftadine, a novel antihistamine, for the prevention of allergic conjunctivitis, a condition characterized by inflammation and itching of the conjunctiva, the thin membrane that lines the inside of the eyelids and covers the white part of the eye. The authors meticulously investigated the in vitro pharmacokinetic properties of alcaftadine, revealing its rapid metabolism and lack of significant plasma protein binding. They also conducted clinical trials to assess the tolerability and efficacy of alcaftadine ophthalmic solutions, finding that it was well tolerated and exhibited a favorable safety profile.

Navigating the Sands of Allergies: Alcaftadine Offers a Promising Solution

This study sheds light on the potential of alcaftadine as a safe and effective treatment option for allergic conjunctivitis. Its favorable pharmacokinetic profile, combined with its good tolerability and safety, make it a promising candidate for further research and clinical application.

Finding Relief in the Oasis of Allergies: Alcaftadine for Conjunctivitis

For individuals suffering from the discomfort and inconvenience of allergic conjunctivitis, alcaftadine offers a potential solution. Its unique properties, including its rapid action and lack of significant side effects, make it a promising treatment option that could bring much-needed relief. However, as with all medications, it's crucial to consult with a healthcare professional to ensure the appropriate use and management of alcaftadine.

Dr. Camel's Conclusion

The desert of allergies can be a challenging and uncomfortable place to navigate. This study offers a glimmer of hope by showcasing the potential of alcaftadine as a safe and effective treatment for allergic conjunctivitis. Its favorable properties make it a promising candidate for providing much-needed relief from the debilitating symptoms of this common condition.

Date :
  1. Date Completed 2011-08-23
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

21314437

DOI: Digital Object Identifier

10.1089/jop.2010.0153

Related Literature

SNS
PICO Info
in preparation
Languages

English

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