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Efficacy and safety of artemehter-lumefantrine in uncomplicated falciparum malaria in Liberia.

Author: AhmadKaleem, AwanMuhammad Younis, KhanSabir Mehmood, KhurshidUmar, RasheedAbdul

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Artemether-lumefantrine combination therapy is safe and effective for the treatment of acute uncomplicated falciparum malaria. The 28-day parasitological cure rate was 100%, and only 10% of patients experienced mild to moderate side effects.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To assess the in vivo efficacy and adverse effects of Artemether-lumefantrine combination in acute uncomplicated falciparum malaria. METHODS: A prospective, observational study was conducted at Department of Medicine and Pathology, Pakistan Medical level II hospital, Tubmanburg and Harpe...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/21375159

データ提供：米国国立医学図書館（NLM）

Efficacy and Safety of Artemether-Lumefantrine in Uncomplicated Falciparum Malaria

This study conducted in Liberia aimed to assess the effectiveness and safety of Artemether-Lumefantrine combination therapy in treating uncomplicated falciparum malaria. The researchers explored the impact of this combination on malaria parasite clearance, fever reduction, and the occurrence of adverse events.

Effective Treatment for Malaria

The study reported a 100% parasitological cure rate after 28 days, suggesting that Artemether-Lumefantrine was highly effective in eliminating the malaria parasite. The combination therapy was also well-tolerated with only mild to moderate side effects in a small percentage of patients.

A Promising Treatment Option

This research sheds light on the potential of Artemether-Lumefantrine as a safe and effective treatment for uncomplicated falciparum malaria, particularly in regions like Liberia where this disease poses a significant health burden. This information could lead to improved treatment strategies for those living in malaria-prone areas.

Dr. Camel's Conclusion

The study's findings are like a cool breeze in the desert of malaria research. Artemether-Lumefantrine offers a valuable tool in the fight against this debilitating disease. Its effectiveness and safety make it a promising weapon in our arsenal, especially in regions facing a high malaria burden.

Date :
  1. Date Completed 2011-03-10
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

21375159

DOI: Digital Object Identifier

2576

Related Literature

Article Analysis
・Side Effects of artemether and lumefantrine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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