An open-label, prospective cohort pilot study to evaluate the efficacy and safety of etanercept in the treatment of moderate to severe plaque psoriasis in patients who have not had an adequate response to adalimumab.

Author: VenderRonald

Paper Details 
Original Abstract of the Article :
The past several years have seen the approval of five different biologic agents for the treatment of moderate to severe plaque psoriasis in the United States and Canada. Psoriasis has proven to be a difficult disease to treat and treatment failures, even with newer biologic therapies, are not uncomm...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/21455550

データ提供:米国国立医学図書館(NLM)

Switching Biologics: A Second Chance for Psoriasis Patients?

The world of psoriasis treatment has witnessed the arrival of several powerful biologics. These drugs, like oases in a vast desert, offer hope to patients struggling with moderate to severe plaque psoriasis. However, not all patients respond well to the first biologic therapy. This study investigates the effectiveness and safety of etanercept, a different biologic agent, in patients who have had an inadequate response to adalimumab. It is a prospective cohort pilot study focusing on patients who have not responded adequately to adalimumab and aims to evaluate the efficacy and safety of etanercept in treating their psoriasis. The study highlights the challenges of treating psoriasis and the need for alternative therapies when initial treatments fail.

Second Time's the Charm? Evaluating the Efficacy of Etanercept

There are limited data available on the effectiveness of switching from one biologic to another in psoriasis treatment. This study provides valuable insights into the potential benefits and risks of using etanercept as a second-line therapy for patients who have not responded well to adalimumab. The study emphasizes the importance of individualized treatment strategies in managing psoriasis and explores the possibility of switching to a different biologic if initial treatment fails.

Exploring New Treatment Options: A Hopeful Step

The findings from this study hold promise for patients with psoriasis who have not responded to initial biologic therapies. The results offer hope that switching to a different biologic agent might be a viable option for achieving improved outcomes. However, further research is needed to fully evaluate the efficacy and safety of etanercept in this context.

Dr.Camel's Conclusion

This study provides valuable information about the potential benefits of switching to a different biologic agent in psoriasis treatment. While more research is needed, the findings suggest a promising avenue for patients who have not responded well to initial therapies.

Date :
  1. Date Completed 2011-09-19
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21455550

DOI: Digital Object Identifier

21455550

Related Literature

SNS
PICO Info
in preparation
Languages

English

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