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VS-105: a novel vitamin D receptor modulator with cardiovascular protective effects.
Author: ChenYung-Wu, KawaiMegumi, NakaneMasaki, Wu-WongJ Ruth
Original Abstract of the Article :
Vitamin D receptor (VDR) modulators (VDRMs) such as calcitriol, paricalcitol and doxercalciferol are commonly used to manage hyperparathyroidism secondary to chronic kidney disease (CKD). CKD patients experience extremely high risks of cardiovascular morbidity and mortality. Clinical observations sh...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188908/
データ提供:米国国立医学図書館(NLM)
VS-105: A Novel Vitamin D Receptor Modulator
This article discusses VS-105, a novel vitamin D receptor modulator (VDRM) with potential cardiovascular protective effects. The study highlights the current limitations of existing VDRMs used to manage hyperparathyroidism secondary to chronic kidney disease (CKD). While these medications have shown cardio-renal protective and survival benefits, hypercalcemia remains a significant concern. This article emphasizes the need for VDRMs with cardiovascular protective effects without the risk of hypercalcemia. VS-105 emerges as a promising candidate, offering potential benefits for CKD patients.
VS-105: A Potential Game-Changer for CKD Patients
The article highlights the potential of VS-105 to address the current limitations of VDRMs. VS-105, with its cardiovascular protective effects and lack of hypercalcemic liability, offers a promising alternative for CKD patients. This research encourages further investigation into the therapeutic potential of VS-105 in managing CKD and its associated cardiovascular complications.
Innovations in CKD Management
This article underscores the need for continued innovation in managing CKD and its associated complications. The development of new VDRMs, such as VS-105, with improved safety profiles and therapeutic benefits holds great promise for improving the lives of CKD patients. This research encourages ongoing research and development to create new and effective treatments for CKD.
Dr. Camel's Conclusion
Imagine a thirsty traveler in a vast desert, seeking a source of hydration that won't burden their journey. VS-105, like a refreshing oasis, offers hope for CKD patients, providing potential cardiovascular protection without the baggage of hypercalcemia. This research encourages us to continue exploring new horizons in CKD management, seeking innovative solutions that can help patients thrive in this challenging landscape.
Date :
- Date Completed 2012-03-20
- Date Revised 2021-10-20
Further Info :
Related Literature
English
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