[Effects of Herba Ephedra Sinicae and Fructus Schisandrae Chinensis on pathology of rats with bleomycin A(5)-induced idiopathic pulmonary fibrosis].

Author: GaoMing-chao, LiuYang, MengFan-yun, OuMin, WangYong-yan, ZhaiHua-qiang, ZhangShuo-feng

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To observe the different effects between Mahuang (Herba Ephedra Sinicae) and Wuweizi (Fructus Schisandrae Chinensis) on the pathological changes of rats with bleomycin A(5)-induced pulmonary fibrosis. METHODS: Ninety Wistar rats were randomly divided into sham operation group, model grou...See full text at original site
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引用元:
https://doi.org/10.3736/jcim20110514

データ提供:米国国立医学図書館(NLM)

Herba Ephedra Sinicae and Fructus Schisandrae Chinensis: A Potential Combination for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by scarring and stiffening of the lung tissue. This study investigates the effects of two traditional Chinese medicines, Herba Ephedra Sinicae and Fructus Schisandrae Chinensis, on bleomycin A(5)-induced pulmonary fibrosis in rats. The research aims to assess the potential therapeutic benefits of these herbal remedies in reducing lung injury and fibrosis, particularly focusing on their impact on pulmonary artery injury, nuclear density, microvessel density, and inner diameter of pulmonary arterioles.

A Potential Herbal Solution for IPF: The Power of Herba Ephedra Sinicae and Fructus Schisandrae Chinensis

The study reveals that a combination of Herba Ephedra Sinicae and Fructus Schisandrae Chinensis can effectively restrain pulmonary artery injury in rats with bleomycin A(5)-induced pulmonary fibrosis. The findings suggest that these herbal remedies can potentially reduce inflammation, improve vascular function, and mitigate fibrosis progression. This research offers a potential avenue for exploring novel therapeutic strategies for managing IPF, leveraging the wisdom of traditional Chinese medicine.

Exploring the Potential of Traditional Chinese Medicine in IPF: A New Frontier

This research highlights the potential of traditional Chinese medicines, such as Herba Ephedra Sinicae and Fructus Schisandrae Chinensis, as therapeutic agents for IPF. The study underscores the need for further investigation into the efficacy and safety of these herbal remedies in treating IPF in humans. This research encourages a broader exploration of traditional medicine practices, recognizing their potential to offer valuable insights and therapeutic solutions for various health conditions.

Dr.Camel's Conclusion

This study provides promising evidence for the potential therapeutic benefits of Herba Ephedra Sinicae and Fructus Schisandrae Chinensis in managing bleomycin A(5)-induced pulmonary fibrosis in rats. The findings suggest that these herbal remedies may offer a novel approach to treating IPF, potentially reducing inflammation, improving vascular function, and mitigating fibrosis progression. Further research is needed to confirm their efficacy and safety in human clinical trials.

Date :
  1. Date Completed 2012-03-12
  2. Date Revised 2019-09-23
Further Info :

Pubmed ID

21565143

DOI: Digital Object Identifier

10.3736/jcim20110514

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PICO Info
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Languages

Chinese

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