Efficacy and safety of administration of oral iron chelator deferiprone in patients with early myelodysplastic syndrome.

Author: CermakJaroslav, HochovaIvana, JonasovaAnna, NeuwirtovaRadana, SiskovaMagda, VondrakovaJana, WalterovaLenka

Paper Details 
Original Abstract of the Article :
Forty-eight patients with early myelodysplastic syndrome (MDS) without excess of blasts, with average initial serum ferritin levels of 2739.5 μg/L (range 825-11287 μg/L), were treated with deferiprone (L1) in a daily dose of 40-90 mg/kg. Median duration of chelation treatment was 10.9 months (range ...See full text at original site
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引用元:
https://doi.org/10.3109/03630269.2011.578515

データ提供:米国国立医学図書館(NLM)

Iron Overload in Myelodysplastic Syndrome: A Desert of Iron

Myelodysplastic syndrome (MDS), like a desert ravaged by drought, can leave the body depleted of vital resources. One such resource is iron, which, when in excess, can further exacerbate the challenges of this complex blood disorder.

This study explores the efficacy and safety of deferiprone, an oral iron chelator, in treating iron overload in patients with early MDS. The researchers, like skilled desert engineers, meticulously analyze the effectiveness of this treatment in removing excess iron from the body, akin to building a complex irrigation system to restore the desert's life-giving water.

Deferiprone: A Potential Oasis in the Desert of Iron

The study found that deferiprone effectively reduced iron stores in many patients with MDS, particularly those with lower initial iron levels. This is like finding a hidden spring that provides a steady supply of water, helping to revitalize the depleted desert. The findings suggest that deferiprone can be a valuable tool for managing iron overload in MDS patients, offering a potential oasis of relief.

Health Implications and Life Applications

This study sheds light on the importance of addressing iron overload in MDS patients, a crucial factor in managing this complex blood disorder. The findings suggest that deferiprone, like a well-designed irrigation system, can help to restore the balance of iron within the body, improving the overall health and well-being of those affected by this disease.

Dr.Camel's Conclusion

MDS, like a parched desert, can leave the body depleted of vital resources, particularly iron. This study reveals the potential of deferiprone, like a carefully constructed irrigation system, to restore the delicate balance of iron, offering a lifeline of hope for those battling this challenging disease.
Date :
  1. Date Completed 2011-09-29
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

21599434

DOI: Digital Object Identifier

10.3109/03630269.2011.578515

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PICO Info
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Languages

English

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