Clinical efficacy and safety of etanercept versus sulfasalazine in patients with ankylosing spondylitis: a randomized, double-blind trial.

Author: BraunJuergen, Burgos-VargasRuben, FreundlichBruce, HuangFeng, KoenigAndrew S, VlahosBonnie, van der Horst-BruinsmaIrene E

Paper Details 
Original Abstract of the Article :
Etanercept, a fully human tumor necrosis factor (TNF) receptor, is an effective treatment in patients with ankylosing spondylitis (AS). Sulfasalazine is frequently used for the treatment of both axial symptoms and peripheral symptoms of AS, and it has been the recommended therapy before the use of a...See full text at original site
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引用元:
https://doi.org/10.1002/art.30223

データ提供:米国国立医学図書館(NLM)

Etanercept vs. Sulfasalazine: A Showdown in the Desert of Ankylosing Spondylitis

Ankylosing spondylitis (AS), a chronic inflammatory disease primarily affecting the spine, can be a relentless desert storm, causing pain and stiffness that can make even the simplest movements feel like an arduous journey. Two medications, etanercept and sulfasalazine, are commonly used to manage this condition, but their relative efficacy and safety have been the subject of much debate, much like a desert oasis disputed by rival tribes. This study, a beacon of light in the desert of AS research, aimed to compare the efficacy and safety of etanercept and sulfasalazine in patients with axial and peripheral manifestations of AS. The researchers carefully designed a randomized, double-blind trial, meticulously tracking the progress of patients receiving either etanercept or sulfasalazine for 16 weeks.

The Oasis of Etanercept: A More Effective Treatment?

This study, like a carefully planned caravan route across the desert, provided valuable insights into the effectiveness of etanercept and sulfasalazine for AS. The results suggest that etanercept may be a more effective treatment than sulfasalazine for both axial and peripheral manifestations of AS. However, it's important to note that this study was relatively short-term and further research is needed to determine the long-term outcomes of each treatment.

Navigating the Desert of Ankylosing Spondylitis: Choosing the Right Oasis

This research highlights the potential benefits of etanercept for individuals with AS. However, it's crucial to remember that every individual's journey through the desert of AS is unique. The best treatment option depends on the severity of the symptoms, individual factors, and potential side effects. Consult with a qualified healthcare provider to discuss your specific situation and create a personalized treatment plan that best meets your needs.

Dr. Camel's Conclusion

This research sheds light on the potential of etanercept as a treatment for AS, offering a potential oasis of relief for those seeking a more effective treatment option. While more research is necessary to fully understand its long-term efficacy and potential side effects, the findings suggest that etanercept may be a valuable tool for managing the symptoms of AS. The journey through the desert of AS is challenging, but with the right guidance and treatment, we can find a path towards a better quality of life.

Date :
  1. Date Completed 2011-08-17
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

21630245

DOI: Digital Object Identifier

10.1002/art.30223

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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