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Clinical utility of denosumab for treatment of bone loss in men and women.

Author: AdlerRobert A, GillRanjodh S

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review discusses denosumab, a humanized monoclonal antibody and antiresorptive agent for the treatment of osteoporosis. Denosumab has demonstrated efficacy in increasing bone mineral density and reducing fracture risk in postmenopausal women and men on androgen deprivation therapy. Denosumab's subcutaneous administration every six months may improve adherence and its shorter duration of action may lead to fewer long-term side effects compared to bisphosphonates.
Paper Details　
Original Abstract of the Article :
While most older patients with osteoporosis are treated with antiresorptive bisphosphonates such as alendronate, risedronate, ibandronate, and zoledronic acid, such drugs have side effects, remain in bone for extended periods, and lead to poor adherence to chronic treatment. Denosumab is a humanized...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131981/

データ提供：米国国立医学図書館（NLM）

Denosumab: A New Frontier in Osteoporosis Treatment

Osteoporosis, a condition characterized by weakened bones, affects millions of people worldwide. This research is like a traveler discovering a new oasis in a vast desert, exploring the potential of denosumab, a monoclonal antibody, as a treatment for osteoporosis. The authors highlight the advantages of denosumab over traditional bisphosphonates, such as its effectiveness in increasing bone mineral density and reducing fractures, as well as its convenient administration schedule. However, they also emphasize the need for long-term studies to fully understand the potential risks and benefits of denosumab.

Denosumab: A Promising New Weapon in the Fight Against Osteoporosis

This research demonstrates the potential of denosumab as a valuable tool in the treatment of osteoporosis. The authors highlight its effectiveness in increasing bone mineral density and reducing fractures, offering a promising alternative to traditional bisphosphonates. This is like discovering a new oasis in a vast desert, providing a much-needed source of hydration and respite for those battling osteoporosis.

Maintaining Bone Health: A Journey Through the Desert

This research emphasizes the importance of maintaining bone health, highlighting the potential benefits of denosumab as a treatment for osteoporosis. It is like a caravan navigating a desert, ensuring the well-being of its travelers by addressing potential health concerns and providing the necessary resources to maintain their health.

Dr.Camel's Conclusion

This research examines the clinical utility of denosumab for the treatment of bone loss in men and women. The authors highlight the potential benefits of denosumab over traditional bisphosphonates, including its effectiveness in increasing bone mineral density and reducing fractures, as well as its convenient administration schedule. This research is like a camel caravan exploring a vast desert, uncovering new and promising solutions for maintaining bone health.
Date :
  1. Date Completed 2011-11-29
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21753866

DOI: Digital Object Identifier

PMC3131981

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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