[Sildenafil therapy for pulmonary hypertension: a prospective study].

Author: ChengXian-sheng, GuQing, HeJian-Guo, LiuZhi-hong, LuXian-ling, NiXin-hai, ShanGuang-liang, XiongChang-ming, ZengWei-jie, ZhaoZhi-hui, ZhuFeng

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To explore the safety and efficacy of oral sildenafil therapy for pulmonary arterial hypertension (PAH), and to provide evidence for sildenafil treatment for Chinese patients with PAH. METHODS: In this 12-week, prospective, open-label, uncontrolled study, 56 patients with PAH were given ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/21781512

データ提供:米国国立医学図書館(NLM)

Sildenafil for Pulmonary Hypertension: A Prospective Study

Pulmonary arterial hypertension (PAH), a serious condition characterized by high blood pressure in the arteries of the lungs, poses significant challenges for patients. This prospective study investigates the safety and efficacy of oral sildenafil therapy for PAH, aiming to provide evidence for its treatment in Chinese patients. The study followed 56 patients with PAH who received oral sildenafil for 12 weeks, evaluating their exercise capacity, functional class, and cardiopulmonary hemodynamics. The researchers meticulously monitored for any signs of clinical worsening. The results demonstrate the potential of sildenafil therapy for improving exercise capacity, functional class, and hemodynamics in patients with PAH, offering a valuable treatment option for a challenging condition.

Sildenafil: A Beacon of Hope for Pulmonary Hypertension Patients

The study demonstrates that sildenafil significantly improves exercise capacity, as measured by the 6-minute walk test, in patients with PAH. Additionally, it promotes improvement in functional class, a measure of the severity of the condition, indicating a positive impact on overall quality of life for PAH patients. The study also highlights the favorable safety profile of sildenafil, with mild side effects consistent with previous reports. The findings suggest that sildenafil therapy offers a promising treatment option for PAH, potentially transforming the lives of patients struggling with this debilitating condition.

Navigating Pulmonary Hypertension: Understanding Treatment Options

If you or a loved one is diagnosed with pulmonary hypertension, consult with a qualified healthcare professional to explore appropriate treatment options. Sildenafil therapy, as demonstrated in this study, may offer a significant improvement in exercise capacity, functional class, and overall quality of life.

Dr. Camel's Conclusion

Imagine a patient with PAH struggling to navigate life's desert, breathless and exhausted. Sildenafil, like a refreshing oasis, offers a potential solution for improving their journey. This study provides valuable insights into the efficacy and safety of sildenafil therapy, potentially transforming the lives of PAH patients by offering a new path towards a more fulfilling life.

Date :
  1. Date Completed 2012-10-18
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21781512

DOI: Digital Object Identifier

21781512

Related Literature

SNS
PICO Info
in preparation
Languages

Chinese

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