Paper Details

  1. Home
  2. Paper Details

Clinical efficacy of propylthiouracil and its influence on prolactin in psoriatic patients.

Author: DayalanHaripriya, ElangoTamilselvi, GnanarajPushpa, MalligarjunanHemamalini, SubramanianSwapna

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Propylthiouracil (PTU) is an effective drug for psoriasis treatment. PTU was found to significantly reduce prolactin levels in psoriatic patients, suggesting an antiproliferative effect on keratinocytes.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Propylthiouracil (PTU) is an effective drug for psoriasis treatment. Prolactin (PRL) is increased during psoriasis which has hyperproliferative effect on keratinocytes. Hence, the objective is to find the effect of PTU on PRL level in psoriatic patients. DESIGN AND METHODS: 25 psoriatic ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.clinbiochem.2011.07.009

データ提供：米国国立医学図書館（NLM）

Propylthiouracil: A Desert Oasis for Psoriasis?

Psoriasis, like a stubborn desert rash, can cause discomfort and affect quality of life. This study investigates the effectiveness of propylthiouracil (PTU), a medication primarily used to treat thyroid disorders, as a treatment for psoriasis, like seeking a hidden oasis in the desert of dermatological research.

PTU: A Potential Treatment for Psoriasis

The study demonstrates that PTU effectively clears psoriatic lesions and reduces prolactin levels, a hormone that contributes to the hyperproliferation of keratinocytes in psoriasis. This finding suggests that PTU may offer a viable treatment option for psoriasis, like discovering a new path through the desert, leading to a more effective and potentially safer treatment approach.

A New Perspective on Psoriasis Treatment

This research provides a new perspective on psoriasis treatment, exploring the potential of medications traditionally used for other conditions. It's like finding a hidden oasis in the desert of psoriasis research, offering a potential source of relief and a pathway towards a healthier skin.

Dr.Camel's Conclusion

This study presents a promising new avenue for psoriasis treatment, highlighting the potential of repurposing existing medications for new applications. It's like finding a hidden oasis in the desert of dermatological research, offering a new source of hope and a pathway towards a healthier future for psoriasis patients.

Date :
  1. Date Completed 2012-03-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21820424

DOI: Digital Object Identifier

10.1016/j.clinbiochem.2011.07.009

Related Literature

Article Analysis
・Side Effects of propylthiouracil
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.