Paper Details

  1. Home
  2. Paper Details

[The treatment of ankylosing spondylitis with auranofin (Ridaura)].

Author: BandillaK, GrasedyckK, SchattenkirchnerM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study found that auranofin was not effective in treating the back pain and stiffness associated with ankylosing spondylitis. While there may be some potential benefit for the arthritis in the arms and legs, further research is needed to confirm this finding. This highlights the need for alternative treatments for the peripheral joint involvement in ankylosing spondylitis.
Paper Details　
Original Abstract of the Article :
Auranofin has no influence on axial skeleton manifestation of ankylosing spondylitis, neither on clinical complaints, nor on function and inflammatory parameters. Peripheral arthritis is possibly influenced positively, but this cannot be stated definitely because of the low number of cases in this s...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/2190436

データ提供：米国国立医学図書館（NLM）

Auranofin: A Limited Role in Ankylosing Spondylitis

The field of [rheumatology] is constantly searching for effective treatments for inflammatory conditions like ankylosing spondylitis, a chronic inflammatory disease that primarily affects the spine. This study investigated the potential of [auranofin], a gold-containing drug, to treat ankylosing spondylitis.

Auranofin's Limited Efficacy: A Desert Mirage

The study found that auranofin had no significant influence on the axial skeletal manifestations of ankylosing spondylitis, including clinical complaints, function, and inflammatory parameters. While some positive effects were observed for peripheral arthritis, the limited sample size made definitive conclusions difficult. It's like a camel searching for water in the desert, only to encounter a mirage that offers false hope.

The Need for Alternative Therapies: A Continuous Search

The study highlights the ongoing need for alternative therapies for ankylosing spondylitis, particularly for the management of peripheral joint involvement. Further research is necessary to explore more effective treatment options for this challenging condition. It's like a camel navigating an unforgiving desert, requiring perseverance and adaptability to find solutions.

Dr.Camel's Conclusion

This study emphasizes the ongoing quest for effective treatments for ankylosing spondylitis. It's like a camel seeking a shortcut through the desert, only to discover that the path ahead is long and arduous. Researchers continue to explore new horizons, hoping to find a cure for this debilitating disease.

Date :
  1. Date Completed 1990-07-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2190436

DOI: Digital Object Identifier

2190436

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.