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Side effects of phenobarbital in epilepsy: a systematic review.

Author: LiYou-Ping, ZengLi-Nan, ZhangLing-Li

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Phenobarbital, an antiepileptic drug, is still widely used, but it can cause cognitive and behavioral side effects.
Paper Details　
Original Abstract of the Article :
In recent years, phenobarbital, as an antiepileptic drug, has become less popular based on adverse events, especially cognitive and behavioural side effects. Despite the development of better tolerated new generation AEDs, phenobarbital is still widely used particularly in developing countries becau...See full text at original site
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引用元：
https://doi.org/10.1684/epd.2011.0444

データ提供：米国国立医学図書館（NLM）

Phenobarbital: A Controversial Antiepileptic Drug

Phenobarbital has been a mainstay in the treatment of epilepsy for decades. However, its use has become more controversial due to concerns about potential side effects. This review examines the safety profile of phenobarbital, exploring the potential cognitive and behavioral side effects associated with its use.

The Dilemma of Phenobarbital: Balancing Benefits and Risks

Despite the development of newer anti-epileptic drugs (AEDs) with fewer side effects, phenobarbital remains a popular choice in many developing countries due to its affordability. It's a classic case of balancing cost-effectiveness with potential risks. This review highlights the need for careful consideration of the risks and benefits of phenobarbital in the context of individual patients.

Understanding the Risks: An Informed Decision

The review emphasizes the importance of understanding the potential side effects of phenobarbital and discussing these concerns with your doctor. It's like a camel navigating a rocky terrain—we need to be aware of the potential pitfalls to avoid potential harm.

Dr.Camel's Conclusion

This review reminds us that the use of phenobarbital, while a valuable tool, must be carefully considered in the context of individual patients. It's like a desert traveler—we need to be aware of the potential risks and benefits before embarking on a journey.

Date :
  1. Date Completed 2012-03-20
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

21926048

DOI: Digital Object Identifier

10.1684/epd.2011.0444

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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