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Use of uridine triacetate for the management of fluorouracil overdose.

Author: McEvillyMargaret, PopelasCarl, TremmelBob

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Uridine triacetate effectively treated a patient who received a fluorouracil overdose. The patient received oral uridine triacetate for five days without experiencing nausea or vomiting. This highlights the potential of uridine triacetate to manage fluorouracil toxicity.
Paper Details　
Original Abstract of the Article :
PURPOSE: The use of uridine triacetate for the management of fluorouracil toxicity is reported. SUMMARY: A 55-year-old man with malignant neoplasm of the sigmoid colon (stage IIIC) was seen in an outpatient chemotherapy center for his first six-month regimen of leucovorin calcium, fluorouracil, and...See full text at original site
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引用元：
https://doi.org/10.2146/ajhp100434

データ提供：米国国立医学図書館（NLM）

Uridine Triacetate: A Potential Oasis for Fluorouracil Overdose

Chemotherapy, a powerful tool in the fight against cancer, can sometimes have unexpected side effects. This study reports the successful use of uridine triacetate in managing fluorouracil overdose. Researchers describe the case of a 55-year-old man who received an overdose of fluorouracil during chemotherapy, and the subsequent use of uridine triacetate to mitigate the toxicity.

Uridine Triacetate: A Promising Intervention for Fluorouracil Overdose

The study demonstrates the potential of uridine triacetate in managing fluorouracil overdose. The patient received uridine triacetate 18 hours after the overdose, and his laboratory values remained stable. This case report suggests that uridine triacetate may offer a valuable intervention in the event of fluorouracil overdose.

Navigating the Desert of Chemotherapy Side Effects

This study highlights the importance of having effective interventions available to manage potential side effects of chemotherapy. It also underscores the need for vigilance in preventing medication errors and ensuring patient safety. Remember, navigating the desert of chemotherapy can be challenging, but with careful attention to detail and timely intervention, we can minimize risks and improve patient outcomes.

Dr.Camel's Conclusion

This study offers a glimmer of hope in the event of fluorouracil overdose. Uridine triacetate emerges as a potential oasis, offering a means to mitigate the toxicity associated with this powerful chemotherapy drug. As we continue to explore this complex landscape, we can strive to develop innovative interventions and enhance patient safety in the battle against cancer.
Date :
  1. Date Completed 2012-02-14
  2. Date Revised 2019-01-01
Further Info :

Pubmed ID

21930638

DOI: Digital Object Identifier

10.2146/ajhp100434

Related Literature

Article Analysis
・Effects of uridine triacetate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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