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Tongue hyperpigmentation resulting from peginterferon alfa-2b and ribavirin treatment in a patient with chronic hepatitis C.
Author: ChawlaYogesh Kumar, DhimanRadha Krishan, DusejaAjay, GhoshSouvik
Original Abstract of the Article :
Hepatitis C virus (HCV) infection has been associated with several cutaneous diseases such as lichen planus, porphyria cutanea tarda, chronic pruritus, and cutaneous necrotizing vasculitis (Doutre, Arch Dermatol 135:1401-1403, 1999). The antiviral treatment for chronic HCV with interferon alfa (INF)...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s10620-011-1914-5
データ提供:米国国立医学図書館(NLM)
Tongue Hyperpigmentation: A Potential Side Effect of Hepatitis C Treatment
This case report explores a potential side effect of peginterferon alfa-2b and ribavirin treatment for chronic hepatitis C: tongue hyperpigmentation. The authors describe a case of tongue hyperpigmentation in a patient with genotype 4 chronic hepatitis C, highlighting the need for awareness of this potential adverse event. The case also provides insights into the diverse cutaneous manifestations associated with hepatitis C infection and its treatment.
The Connection Between Treatment and Tongue Hyperpigmentation
The case report suggests a potential link between the combination therapy of peginterferon alfa-2b and ribavirin and the development of tongue hyperpigmentation. While this adverse effect is not commonly reported, it highlights the need for vigilance in monitoring patients receiving this treatment. Further research is required to better understand the mechanisms underlying this side effect and to identify potential risk factors.
The Importance of Patient Monitoring
This case underscores the importance of careful monitoring of patients receiving antiviral treatment for hepatitis C, particularly for potential cutaneous side effects. Early detection and management of these adverse events can help prevent discomfort and improve patient outcomes.
Dr.Camel's Conclusion
This case report is like a lone oasis in the desert, reminding us that even seemingly common treatments can have unexpected consequences. The link between peginterferon alfa-2b and ribavirin treatment and tongue hyperpigmentation highlights the need for vigilance in monitoring patients and understanding the potential side effects of medications. It's a reminder that the desert of medical knowledge is vast, and there's always more to learn about the intricate relationships between medications and the human body.
Date :
- Date Completed 2012-04-10
- Date Revised 2021-10-20
Further Info :
English
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