Tongue hyperpigmentation resulting from peginterferon alfa-2b and ribavirin treatment in a patient with chronic hepatitis C.

Author: ChawlaYogesh Kumar, DhimanRadha Krishan, DusejaAjay, GhoshSouvik

Paper Details 
Original Abstract of the Article :
Hepatitis C virus (HCV) infection has been associated with several cutaneous diseases such as lichen planus, porphyria cutanea tarda, chronic pruritus, and cutaneous necrotizing vasculitis (Doutre, Arch Dermatol 135:1401-1403, 1999). The antiviral treatment for chronic HCV with interferon alfa (INF)...See full text at original site
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引用元:
https://doi.org/10.1007/s10620-011-1914-5

データ提供:米国国立医学図書館(NLM)

Tongue Hyperpigmentation: A Potential Side Effect of Hepatitis C Treatment

This case report explores a potential side effect of peginterferon alfa-2b and ribavirin treatment for chronic hepatitis C: tongue hyperpigmentation. The authors describe a case of tongue hyperpigmentation in a patient with genotype 4 chronic hepatitis C, highlighting the need for awareness of this potential adverse event. The case also provides insights into the diverse cutaneous manifestations associated with hepatitis C infection and its treatment.

The Connection Between Treatment and Tongue Hyperpigmentation

The case report suggests a potential link between the combination therapy of peginterferon alfa-2b and ribavirin and the development of tongue hyperpigmentation. While this adverse effect is not commonly reported, it highlights the need for vigilance in monitoring patients receiving this treatment. Further research is required to better understand the mechanisms underlying this side effect and to identify potential risk factors.

The Importance of Patient Monitoring

This case underscores the importance of careful monitoring of patients receiving antiviral treatment for hepatitis C, particularly for potential cutaneous side effects. Early detection and management of these adverse events can help prevent discomfort and improve patient outcomes.

Dr.Camel's Conclusion

This case report is like a lone oasis in the desert, reminding us that even seemingly common treatments can have unexpected consequences. The link between peginterferon alfa-2b and ribavirin treatment and tongue hyperpigmentation highlights the need for vigilance in monitoring patients and understanding the potential side effects of medications. It's a reminder that the desert of medical knowledge is vast, and there's always more to learn about the intricate relationships between medications and the human body.

Date :
  1. Date Completed 2012-04-10
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21948358

DOI: Digital Object Identifier

10.1007/s10620-011-1914-5

SNS
PICO Info
in preparation
Languages

English

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