Paper Details
- Home
- Paper Details
The B-Raf status of tumor cells may be a significant determinant of both antitumor and anti-angiogenic effects of pazopanib in xenograft tumor models.
Author: AnwarTalha, BernardoMarcelino, ChoykePeter, GrilBrunilde, IlevaLilia, LiewehrDavid J, PalmieriDiane, QianYong, SteegPatricia S, SteinbergSeth M
Original Abstract of the Article :
Pazopanib is an FDA approved Vascular Endothelial Growth Factor Receptor inhibitor. We previously reported that it also inhibits tumor cell B-Raf activity in an experimental brain metastatic setting. Here, we determine the effects of different B-Raf genotypes on pazopanib efficacy, in terms of prima...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187787/
データ提供:米国国立医学図書館(NLM)
Pazopanib: A Targeted Therapy for B-Raf-Driven Cancers
This study delves into the exciting world of [targeted cancer therapies], focusing on the drug [pazopanib]. The researchers investigated the effect of [pazopanib] on different types of [cancer cells] with varying mutations in the [B-Raf] gene. They found that [pazopanib] was particularly effective in inhibiting [tumor growth] in cells with specific [B-Raf] mutations. This discovery highlights the potential of [pazopanib] as a targeted therapy for certain types of [cancer].
Precision Medicine: Tailoring Treatments to Individual Needs
This study underscores the growing importance of [precision medicine] in cancer treatment. By understanding the specific genetic makeup of a tumor, doctors can choose the most effective treatment for each individual patient. This approach has the potential to improve treatment outcomes and minimize side effects.
Cancer Treatment: A Personal Journey
This research offers a glimmer of hope for patients with certain types of [cancer]. However, it's crucial to remember that [cancer treatment] is a personal journey that requires ongoing monitoring and collaboration between patients and healthcare professionals. Open communication and a personalized approach can empower patients to make informed decisions about their treatment and maximize their chances of a successful outcome.
Dr.Camel's Conclusion
This study is like a compass guiding us through the vast desert of [cancer research]. By targeting specific genetic mutations, we can personalize treatment and navigate towards a brighter future for patients!
Date :
- Date Completed 2012-02-13
- Date Revised 2021-12-03
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.