Combined treatment with bicalutamide and anastrozole in a young boy with peripheral precocious puberty due to McCune-Albright Syndrome.

Author: FioreLudovica, LalaRoberto, MatarazzoPatrizia, MussaAlessandro, TessarisDaniele, TuliGerdi, VernaFrancesca

Paper Details 
Original Abstract of the Article :
McCune-Albright Syndrome (MAS) is a congenital endocrine disorder due to mosaic tissutal hyper-function. We describe a boy with a molecularly confirmed MAS, clinically evident with congenital café-au-lait spots, bone fibrous dysplasia, hyperthyroidism, and renal phosphate wasting syndrome. At 4.6 ...See full text at original site
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引用元:
https://doi.org/10.1507/endocrj.ej11-0214

データ提供:米国国立医学図書館(NLM)

McCune-Albright Syndrome: A Case Study of Combined Treatment with Bicalutamide and Anastrozole

McCune-Albright Syndrome (MAS) is a rare genetic disorder, often leaving patients lost in a desert of health challenges. This study presents a case report of a young boy diagnosed with MAS and experiencing precocious puberty. The researchers treated the boy with a combination of bicalutamide, an androgen receptor blocker, and anastrozole, an aromatase inhibitor. This combined approach aimed to control the premature development of secondary sexual characteristics associated with MAS.

Navigating the Challenges of Precocious Puberty: A Combined Approach

The combined treatment of bicalutamide and anastrozole resulted in significant improvement in the boy's condition. The treatment effectively normalized his growth velocity, reduced penile androgenization, and stabilized testicular volume. These positive results demonstrate the potential of this combined approach for treating precocious puberty in patients with MAS. This treatment strategy, like finding a reliable caravan route through a treacherous desert, offers a path toward managing the challenges of this complex condition.

The Importance of Personalized Care: A Journey of Hope

This case study underscores the importance of individualized treatment plans for patients with rare disorders. The researchers' careful approach, involving a combination of medications and close monitoring, provides valuable insights into the management of MAS. This research, like a guiding star in a dark desert night, offers hope and encouragement to patients with MAS and their families.

Dr. Camel's Conclusion

This case report highlights the importance of individualized treatment strategies for rare disorders. The combined use of bicalutamide and anastrozole offers a promising approach for treating precocious puberty in patients with MAS, demonstrating the potential of carefully tailored interventions to navigate the challenges of this complex condition.

Date :
  1. Date Completed 2012-07-02
  2. Date Revised 2019-09-07
Further Info :

Pubmed ID

22068112

DOI: Digital Object Identifier

10.1507/endocrj.ej11-0214

Related Literature

SNS
PICO Info
in preparation
Languages

English

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