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[Observational retrospective study to evaluate the effectiveness and safety of treatment schemes with bortezomib for multiple myeloma in our hospital].

Author: Iranzo FernándezM D, León-VillarJ, Moreno BelmonteM J, Titos-ArcosJ C, de Arriba de la FuenteF

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Bortezomib is an effective and safe treatment for multiple myeloma with response rates and side effects comparable to published data, although the conditions for using it in clinical practice are not yet recognized in the guidelines for use.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To analyse therapeutic regimens including bortezomib used in our centre for the treatment of multiple myeloma, to evaluate its effectiveness and safety in clinical practice in our hospital, and to assess the appropriateness of the indications described in guidelines. MATERIAL AND METHOD...See full text at original site
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引用元：
https://doi.org/10.1016/j.farma.2011.06.019

データ提供：米国国立医学図書館（NLM）

Bortezomib: A Promising Treatment for Multiple Myeloma

Multiple myeloma, a complex and often challenging cancer, can be likened to a shifting sand dune – constantly evolving and requiring innovative treatment strategies. This research examines the effectiveness and safety of bortezomib, a powerful drug used in the treatment of multiple myeloma. The study explores the clinical use of bortezomib in a real-world setting, analyzing its impact on patient outcomes.

Bortezomib Shows Positive Results in Multiple Myeloma Treatment

The study observed high overall response rates for patients treated with regimens incorporating bortezomib, both in first-line and salvage treatment settings. The response rates observed in this study are comparable to those reported in previous research, further highlighting the potential of bortezomib as a valuable treatment option for multiple myeloma. While the overall response to bortezomib is promising, the study also recognizes the need for further research to better understand the optimal conditions for its use in clinical practice.

Navigating the Side Effects of Bortezomib

Like navigating a treacherous desert, treating multiple myeloma requires a careful balance. This study highlights the importance of considering the potential side effects of bortezomib, including neurotoxicity and gastrointestinal toxicity. While the effectiveness of bortezomib is undeniable, it is essential to weigh its benefits against its potential risks. This research underscores the need for a personalized approach, considering individual patient factors and potential side effects.

Dr. Camel's Conclusion

This study provides a comprehensive overview of the role of bortezomib in the treatment of multiple myeloma, revealing its effectiveness and highlighting the importance of careful patient monitoring. While bortezomib offers a valuable tool in the fight against this challenging disease, it is crucial to remain vigilant about potential side effects and to continue exploring the optimal conditions for its use in clinical practice.
Date :
  1. Date Completed 2013-01-17
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

22115856

DOI: Digital Object Identifier

10.1016/j.farma.2011.06.019

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