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QT prolongation and torsade de pointes induced by fluoroquinolones: infrequent side effects from commonly used medications.

Author: AgarwalVikram, BriasoulisAlexandros, PierceWalter J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Fluoroquinolones can prolong the QT interval, with moxifloxacin carrying the greatest risk. The overall risk of TdP is small, but clinicians should use caution in patients with predisposing factors.
Paper Details　
Original Abstract of the Article :
Although very useful agents, fluoroquinolones are associated with a number of adverse events, some with considerable clinical significance. Prolongation of the QT interval, for example, is an adverse effect associated with the use of fluoroquinolones. Fluoroquinolones prolong the QT interval by bloc...See full text at original site
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引用元：
https://doi.org/10.1159/000334441

データ提供：米国国立医学図書館（NLM）

Fluoroquinolones and QT Prolongation: A Balancing Act

Fluoroquinolones, a class of antibiotics, are effective in treating various infections, but they can also pose risks. This study focuses on the potential adverse effect of QT prolongation, a heart rhythm disturbance, associated with fluoroquinolone use. The study examines the risk of QT prolongation and torsades de pointes (TdP) associated with different fluoroquinolones, highlighting moxifloxacin as carrying the greatest risk. The research emphasizes the need for caution when prescribing these medications, particularly in patients with predisposing factors for TdP.

Navigating the Risks of Fluoroquinolones

This study emphasizes the importance of balancing the benefits and risks of fluoroquinolone use. The research provides valuable information for healthcare professionals to make informed decisions about prescribing these medications, minimizing the risk of potentially life-threatening side effects. The study emphasizes the need for careful patient selection and monitoring to ensure safe and effective treatment.

Fluoroquinolones: A Balancing Act

Imagine a delicate balance between the benefits of a powerful antibiotic and the potential risks associated with it. This study delves into the nuances of fluoroquinolone use, highlighting the importance of understanding the potential risks of QT prolongation and TdP. It encourages healthcare professionals to be mindful of patient-specific factors and exercise caution when prescribing these medications.

Dr.Camel's Conclusion

This research sheds light on the potential risks associated with fluoroquinolone use, specifically QT prolongation and TdP. The study emphasizes the need for careful patient selection and monitoring to ensure the safe and effective use of these valuable antibiotics. It underscores the importance of weighing the benefits and risks of medication, particularly in the context of potential cardiovascular complications.
Date :
  1. Date Completed 2012-02-28
  2. Date Revised 2011-12-22
Further Info :

Pubmed ID

22156660

DOI: Digital Object Identifier

10.1159/000334441

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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