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Design of the Trial to Assess Chelation Therapy (TACT).

Author: BoineauRobin, DriskoJeanne A, GoertzChristine, LamasGervasio A, LeeKerry L, MarkDaniel B, NahinRichard L, RozemaTheodore

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This article describes the design of the TACT clinical trial, which is investigating the benefits and risks of disodium EDTA chelation therapy and a high-dose multivitamin and mineral supplement for cardiovascular disease. The trial is designed to have 85% power to detect a 25% relative reduction in the primary end point.
Paper Details　
Original Abstract of the Article :
TACT is an National Institutes of Health-sponsored, randomized, double-blind, placebo-controlled, 2 × 2 factorial clinical trial testing the benefits and risks of 40 infusions of a multicomponent disodium EDTA chelation solution compared with placebo and of an oral, high-dose multivitamin and minera...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/22172430

データ提供：米国国立医学図書館（NLM）

The Trial to Assess Chelation Therapy (TACT): Unveiling the Potential of Chelation Therapy

The field of cardiovascular health is constantly seeking novel therapies for preventing and treating heart disease. Chelation therapy, a procedure that removes heavy metals from the body, has been investigated for its potential benefits in cardiovascular health. This study, sponsored by the National Institutes of Health, is a large-scale clinical trial exploring the efficacy and safety of chelation therapy in patients with heart disease. The study design is rigorous, with a randomized, double-blind, placebo-controlled approach, and will follow a large cohort of patients for an average of four years. The primary endpoint is a composite measure of cardiovascular events, including mortality, heart attack, stroke, and hospitalization for angina.

The Potential of Chelation Therapy

This trial aims to provide definitive evidence on the effectiveness of chelation therapy in reducing cardiovascular risks. With a substantial sample size and a rigorous design, this study has the power to make a significant impact on how we approach cardiovascular health. If chelation therapy proves effective, it could revolutionize the way we prevent and treat heart disease, offering new hope to millions of people around the world.

Navigating Cardiovascular Health: A Desert of Knowledge

This research highlights the importance of rigorous scientific inquiry in exploring potential therapies for cardiovascular health. Chelation therapy's potential benefits are still under investigation, and it is crucial to approach this therapy with a critical eye, evaluating the evidence with a discerning mind. The results of this study will be crucial in shaping our understanding of chelation therapy and its role in cardiovascular care.

Dr.Camel's Conclusion

The TACT trial is a beacon of hope for those seeking new ways to combat heart disease. By rigorously evaluating chelation therapy, this study will provide valuable insights that could pave the way for better cardiovascular health in the future.

Date :
  1. Date Completed 2012-02-10
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22172430

DOI: Digital Object Identifier

NIHMS331376

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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