A prospective, randomized, double-blind study comparing the efficacy of diltiazem, glyceryl trinitrate, and lidocaine for the treatment of anal fissure in children.

Author: AydinogluAsim, BalciogluMehmet Emin, BolekenMehmet Emin, CevikMuazez, KaradagCetin Ali, KorukIbrahim, OcalServet

Paper Details 
Original Abstract of the Article :
PURPOSE: Anal fissure (AF) is a common perianal condition in children. Although adult patients with AF have been treated successfully using diltiazem, it has not been studied in children. The present randomized, prospective, double-blind study assessed the response, side effects, and recurrence of d...See full text at original site
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引用元:
https://doi.org/10.1007/s00383-011-3048-4

データ提供:米国国立医学図書館(NLM)

Anal Fissure in Children: A New Hope in Diltiazem

The world of pediatric medicine is a fascinating one, filled with unique challenges. Anal fissure, a common perianal condition in children, can be a source of discomfort and distress. This study dives deep into the treatment of anal fissure in children, exploring the efficacy of diltiazem, glyceryl trinitrate, and lidocaine. Utilizing a randomized, prospective, double-blind study, the authors compared the healing rates, side effects, and recurrence of these medications. Their findings revealed that diltiazem emerged as a promising treatment option, demonstrating a significantly higher healing rate compared to the other groups. The study also highlighted the low recurrence rate associated with diltiazem, making it an attractive choice for long-term management.

Diltiazem: A Beacon of Hope for Anal Fissure in Children

The results of this study show that diltiazem, a calcium channel blocker, is a safe and effective treatment for anal fissure in children. The healing rate for those treated with diltiazem was notably higher than those treated with glyceryl trinitrate or lidocaine, especially after a second 8-week course. Furthermore, the study revealed that diltiazem had a significantly lower recurrence rate compared to the other groups. These findings suggest that diltiazem may be a valuable tool in the treatment of anal fissure in children, offering relief from discomfort and potential long-term benefits.

Anal Fissure: A Gentle Reminder of Our Fragility

Anal fissures, like cracks in a parched desert landscape, can be a painful reminder of our vulnerability. This study provides a glimmer of hope for children suffering from this condition, offering a potential solution in diltiazem. However, it's important to note that the study was limited in scope and further research is needed to confirm its effectiveness. Consult with a medical professional for personalized advice and treatment options.

Dr.Camel's Conclusion

This research is a shining example of how science can help us navigate the complex world of pediatric medicine. Diltiazem offers a potentially effective and safe treatment for anal fissures in children, a condition that can be challenging to manage. However, like a mirage in the desert, the findings require further exploration to ensure their reliability. Remember, seeking expert medical advice is crucial for the best possible care.

Date :
  1. Date Completed 2012-07-23
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22212494

DOI: Digital Object Identifier

10.1007/s00383-011-3048-4

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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