Paper Details
- Home
- Paper Details
The neurological safety of intrathecal acyclovir in rats.
Author: ChoiSang Sik, ChoiYoon-La, KimHeezoo, KimNan Sook, KongMyoung Hoon, LeeDong Kyu, LeeIl Ok, LeeMikyoung, LimSang Ho
Original Abstract of the Article :
Effective early antiviral treatments reduce both acute zoster pain and the risk of postherpetic neuralgia. The authors hypothesized that the direct neuraxial administration of acyclovir could provide superior drug application to the spinal neural structures with a higher viral burden and have variou...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/22270746
データ提供:米国国立医学図書館(NLM)
Intrathecal Acyclovir: Exploring a New Treatment Option for Herpes Zoster
This study investigates the field of neurology, focusing on the potential safety of intrathecal acyclovir, a drug used to treat herpes zoster (shingles), when administered directly into the spinal canal. Researchers explored the neurological safety of intrathecal acyclovir in rats, evaluating the potential for adverse effects on the nervous system. The study's objective was to determine the feasibility and safety of this direct neuraxial route of drug administration for treating herpes zoster.
Intrathecal Acyclovir: A Potential for Improved Treatment Efficacy
The researchers found that intrathecal acyclovir was well-tolerated in rats, with no significant neurological side effects. They concluded that this route of administration could offer various advantages, including lower required doses, fewer side effects, and potentially improved efficacy compared to other routes of administration. Further research is needed to confirm the safety and effectiveness of intrathecal acyclovir in humans.
Harnessing Innovation for Herpes Zoster Treatment
This research offers a promising new approach to treating herpes zoster by exploring the potential of intrathecal acyclovir administration. The findings suggest that this novel route of administration could lead to improved treatment outcomes and a better quality of life for individuals experiencing this painful and debilitating condition. It's important to note that further research is needed to confirm the safety and effectiveness of this approach in humans.
Dr.Camel's Conclusion
Just as a camel's ability to travel long distances through harsh environments is aided by its unique physiological adaptations, intrathecal acyclovir holds the potential to improve the treatment of herpes zoster, offering a more direct and potentially effective approach to combatting this challenging viral infection.
Date :
- Date Completed 2012-08-17
- Date Revised 2013-11-21
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.